High-Sensitivity, High-Resolution Detection of Reactive Oxygen Species Concentration Using NV Centers

Citation:

Yoav Ninio, Nir Waiskopf, Idan Meirzada, Yoav Romach, Galya Haim, Shira Yochelis, Uri Banin, and Nir Bar-Gill. 2021. “High-Sensitivity, High-Resolution Detection of Reactive Oxygen Species Concentration Using NV Centers.” ACS Photonics, 8, 7, Pp. 1917–1921. Publisher's Version Copy at http://www.tinyurl.com/yh2ymjuy

Abstract:

ACSPhoto_2021Nitrogen-vacancy (NV) color centers in diamond have been demonstrated as useful magnetic sensors, in particular for measuring spin fluctuations and achieving high sensitivity and spatial resolution. These abilities can be used to explore various biological and chemical processes, catalyzed by reactive oxygen species (ROS). Here we demonstrate a novel approach to measure and quantify hydroxyl radicals with high spatial resolution, using the fluorescence difference between NV charged states. According to the results, the achieved NV sensitivity is , realized in situ without spin labels and localized to a volume of ∼10 picoliters.

Notes:

doi: 10.1021/acsphotonics.1c00431
Last updated on 08/14/2021