Uttering a vow was an important and popular religious practice in ancient Judaism. It is mentioned frequently in biblical literature, and an entire rabbinic tractate, Nedarim , is devoted to this subject. In this article, I argue that starting from the Second Temple period, alongside the regular use of the vow, vows were also used as an aggressive binding mechanism in interpersonal situations. This practice became so popular that in certain contexts the vow became synonymous with the curse, as in a number of ossuaries in Jerusalem and in the later Aramaic incantation bowls. Moreover, this semantic expansion was not an isolated Jewish phenomenon but echoed both the use of the anathema in the Pauline epistles and contemporary Greco-Roman and Babylonian magical practices.
Can a clear path be sketched from Wagner’s music to Auschwitz? Can one artist’s work shape history? Wagner’s oeuvre was beloved by Hitler and played in the concentration camps, accompanying unspeakable acts of cruelty. But is that the composer’s fault?
It is not an understatement to say that the interplay between water and protein is a fundamental aspect of life. The vitality of an organism depends on the functionality of its biological machinery, and this, in turn, is mediated in water. Yet, we understand surprisingly little about the nature of the interface between bulk water and the protein. On the one hand, we know that the nature of the bulk water is dominated by the existence of H-bonding and H-bonded networks. On the other hand, the protein surface, where much of the bioactivity is centered, is a complex landscape of hydrophilic and hydrophobic elements. So how does the interface between these two entities work and how do they influence each other? The question is important because if one understands how a particular protein interface influences the dynamics of the water, it then becomes an easily accessible marker for similar behavior in other protein systems. The dielectric relaxation of hydrated proteins with different structures, lysozyme, collagen, and phycocyanin, has been reviewed in this paper. The dynamics of hydrated water was analyzed in terms of orientation and the ionic defect migration model. This approach enables to characterize the microscopic relaxation mechanism of the dynamics of hydration water on the different structures of the protein. In addition, our model is also capable of characterizing not only hydrated proteins but also polymer-water systems.
Advances in commercial wearable devices are increasingly facilitating the collection and analysis of everyday physiological data. This article discusses the theoretical and practical aspects of using such ambulatory devices for the detection of episodic changes in physiological signals as a marker for mental state in outdoor environments. A pilot study was conducted to evaluate the feasibility of using commercial wearables in combination with location tracking technologies. The study measured physiological signals for fifteen participants, including heart rate, heart rate variability, and skin conductance. Participants? signals were recorded during an outdoor walk that was tracked using a Global Positioning System logger. The walk was designed to pass through various types of environments including green, blue, and urban spaces, as well as a more stressful road crossing. The data that were obtained were used to demonstrate how biosensor information can be contextualized and enriched using location information. Significant episodic changes in physiological signals under real-world conditions were detectable in the stressful road crossing but not in the other types of environments. The article concludes that despite challenges and limitations of current off-the-shelf wearables, the utilization of these devices offers novel opportunities for evaluating episodic changes in physiological signals as a marker for mental state during everyday activities including in outdoor environments. Key Words: electrodermal activity, GPS, mental state, stress, wearable.
Advances in commercial wearable devices are increasingly facilitating the collection and analysis of everyday physiological data. This article discusses the theoretical and practical aspects of using such ambulatory devices for the detection of episodic changes in physiological signals as a marker for mental state in outdoor environments. A pilot study was conducted to evaluate the feasibility of using commercial wearables in combination with location tracking technologies. The study measured physiological signals for fifteen participants, including heart rate, heart rate variability, and skin conductance. Participants? signals were recorded during an outdoor walk that was tracked using a Global Positioning System logger. The walk was designed to pass through various types of environments including green, blue, and urban spaces, as well as a more stressful road crossing. The data that were obtained were used to demonstrate how biosensor information can be contextualized and enriched using location information. Significant episodic changes in physiological signals under real-world conditions were detectable in the stressful road crossing but not in the other types of environments. The article concludes that despite challenges and limitations of current off-the-shelf wearables, the utilization of these devices offers novel opportunities for evaluating episodic changes in physiological signals as a marker for mental state during everyday activities including in outdoor environments. Key Words: electrodermal activity, GPS, mental state, stress, wearable.
We examine the drivers of the convergence of the hourly wage distributions of males and females in Israel between 1995 and 2008. Israel is an interesting case study in this respect, since it experienced declining wage inequality in recent decades, as opposed to most developed countries. We found that the gender differences in both average wages and wage inequality declined over time. In particular, average wages increased faster for females than for males, while wage inequality declined faster for males than for females. We decomposed these distributional changes into the contributions of worker and job attributes, the returns on these attributes and residuals using a Shapley approach applied to counterfactual simulated wage distributions. We found that most of the increase in male wages was due to the increase in wages of workers in high-wage occupations and industries, while female wages increased mostly due to the increase in the returns to experience. The decline in wage inequality was driven mostly by changes in attributes, the decline in the returns to education, and the catching-up of immigrant workers, and each of these components was stronger for males than for females. We conclude that the convergence of the male and female wage distributions was due to both changes in the supply of labor, especially among females, and changes in the demand for labor leading to changes in the returns to various skills.
A major challenge of contemporary neuroscience is to unravel the structure of the connectome, the ensemble of neural connections that link between different functional units of the brain, and to reveal how this structure relates to brain function. This thriving area of research largely follows the general tradition in biology of reverse-engineering, which consists of first observing and characterizing a biological system or process, and then deconstructing it into its fundamental building blocks in order to infer its modes of operation. However, a complementary form of biology has emerged, synthetic biology, which emphasizes construction-based forward-engineering. The synthetic biology approach comprises the assembly of new biological systems out of elementary biological parts. The rationale is that the act of building a system can be a powerful method for gaining deep understanding of how that system works. As the fields of connectomics and synthetic biology are independently growing, I propose to consider the benefits of combining the two, to create synthetic connectomics, a new form of neuroscience and a new form of synthetic biology. The goal of synthetic connectomics would be to artificially design and construct the connectomes of live behaving organisms. Synthetic connectomics could serve as a unifying platform for unraveling the complexities of brain operation and perhaps also for generating new forms of artificial life, and, in general, could provide a valuable opportunity for empirically exploring theoretical predictions about network function. What would a synthetic connectome look like? What purposes would it serve? How could it be constructed? This review delineates the novel notion of a synthetic connectome and aims to lay out the initial steps towards its implementation, contemplating its impact on science and society.
