2019
Akram Obiedat, Seidel, Einat , Mahameed, Mohamed , Berhani, Orit , Tsukerman, Pinchas , Voutetakis, Konstantinos , Chatziioannou, Aristotelis , McMahon, Mari , Avril, Tony , Chevet, Eric , Mandelboim, Ofer , ו Tirosh, Boaz . 2019.
“Transcription Of The Nkg2D Ligand Mica Is Suppressed By The Ire1/Xbp1 Pathway Of The Unfolded Protein Response Through The Regulation Of E2F1.”. Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology, 33, 3, Pp. 3481–3495. doi:10.1096/fj.201801350RR.
תקציר The unfolded protein response (UPR) is an adaptive signaling pathway activated in response to endoplasmic reticulum (ER) stress. The effectors of the UPR are potent transcription activators; however, some genes are suppressed by ER stress at the mRNA level. The mechanisms underlying UPR-mediated gene suppression are less known. Exploration of the effect of UPR on NK cells ligand expression found that the transcription of NK group 2 member D (NKG2D) ligand major histocompatibility complex class I polypeptide-related sequence A/B (MICA/B) is suppressed by the inositol-requiring enzyme 1 (IRE1)/X-box binding protein 1 (XBP1) pathway of the UPR. Deletion of IRE1 or XBP1 was sufficient to promote mRNA and surface levels of MICA. Accordingly, NKG2D played a greater role in the killing of IRE1/XBP1 knockout target cells. Analysis of effectors downstream to XBP1s identified E2F transcription factor 1 (E2F1) as linking UPR and MICA transcription. The inverse correlation between XBP1 and E2F1 or MICA expression was corroborated in RNA-Seq analysis of 470 primary melanoma tumors. While mechanisms that connect XBP1 to E2F1 are not fully understood, we implicate a few microRNA molecules that are modulated by ER stress and possess dual suppression of E2F1 and MICA. Because of the importance of E2F1 and MICA in cancer progression and recognition, these observations could be exploited for cancer therapy by manipulating the UPR in tumor cells.-Obiedat, A., Seidel, E., Mahameed, M., Berhani, O., Tsukerman, P., Voutetakis, K., Chatziioannou, A., McMahon, M., Avril, T., Chevet, E., Mandelboim, O., Tirosh, B. Transcription of the NKG2D ligand MICA is suppressed by the IRE1/XBP1 pathway of the unfolded protein response through the regulation of E2F1.
Inbal Herold, Kowbel, David , Delgado-Álvarez, Diego L. , Garduño-Rosales, Marisela , Mouriño-Pérez, Rosa R. , ו Yarden, Oded . 2019.
“Transcriptional Profiling And Localization Of Gul-1, A Cot-1 Pathway Component, In Neurospora Crassa”. Fungal Genetics And Biology, 126, Pp. 1 - 11. doi:https://doi.org/10.1016/j.fgb.2019.01.010.
Publisher's Version תקציר Impairment of theNeurospora crassaCOT-1 kinase results in defects in hyphal polarity. Some of these effects are partially suppressed by inactivation of gul-1 (encoding an mRNA-binding protein involved in translational regulation). Here, we report on the transcriptional profiling of cot-1 inactivation and demonstrate that gul-1 affects transcript abundance of multiple genes in the COT-1 pathway, including processes such as cell wall remodeling, nitrogen and amino acid metabolism. The GUL-1 protein itself was found to be distributed within the entire hyphal cell, along with a clear presence of aggregates that traffic within the cytoplasm. Live imaging of GUL-1-GFP demonstrated that GUL-1 transport is microtubule-dependent. Cellular stress, as imposed by the presence of the cell wall biosynthesis inhibitor Nikkomycin Z or by nitrogen limitation, resulted in a 2–3-fold increase of GUL-1 aggregate association with nuclei. Taken together, this study demonstrates that GUL-1 affects multiple processes, its function is stress-related and linked with cellular traffic and nuclear association.
G. Gabay, Faigenboim, A. , Dahan, Y. , Izhaki, Y. , Itkin, M. , Malitsky, S. , Elkind, Yonatan , ו Flaishman, M.A.. 2019.
“Transcriptome Analysis And Metabolic Profiling Reveal The Key Role Of Α-Linolenic Acid In Dormancy Regulation Of European Pear”. Journal Of Experimental Botany, 70, 3, Pp. 734-737. doi:10.1093/jxb/ery405.
Publisher's Version תקציר Deciduous trees require sufficient chilling during winter dormancy to grow. To decipher the dormancy-regulating mechanism, we carried out RNA sequencing (RNA-Seq) analysis and metabolic profiling of European pear (Pyrus communis L.) vegetative buds during the dormancy phases. Samples were collected from two cultivars that differed greatly in their chilling requirements: Spadona' (SPD), a low chilling requirement cultivar; and Harrow Sweet (HS), a high chilling requirement cultivar. Comparative transcriptome analysis revealed >8500 differentially expressed transcripts; most were related to metabolic pathways. Out of 174 metabolites, 44 displayed differential levels in both cultivars, 38 were significantly changed only in SPD, and 15 only in HS. Phospholipids were mostly accumulated at the beginning of dormancy, sugars between before dormancy and mid-dormancy, and fatty acids, including α-linolenic acid, at dormancy break. Differentially expressed genes underlying previously identified major quantitative trait loci (QTLs) in linkage group 8 included genes related to the α-linolenic acid pathway, 12-oxophytodienoate reductase 2-like, and the DORMANCY-ASSOCIATED MADS-BOX (DAM) genes, PcDAM1 and PcDAM2, putative orthologs of PpDAM1 and PpDAM2, confirming their role for the first time in European pear. Additional new putative dormancy-related uncharacterized genes and genes related to metabolic pathways are suggested. These results suggest the crucial role of α-linolenic acid and DAM genes in pear bud dormancy phase transitions. © 2018 The Author(s).
Vijaya KR Vulavala, Fogelman, Edna , Faigenboim, Adi , Shoseyov, Oded , ו Ginzberg, Idit . 2019.
“The Transcriptome Of Potato Tuber Phellogen Reveals Cellular Functions Of Cork Cambium And Genes Involved In Periderm Formation And Maturation”. Sci Rep, 9, 1, Pp. 10216. doi:10.1038/s41598-019-46681-z.
תקציר The periderm is a protective corky tissue that is formed through the cambial activity of phellogen cells, when the outer epidermis is damaged. Timely periderm formation is critical to prevent pathogen invasion and water loss. The outer layers of the potato periderm, the tuber skin, serves as a model to study cork development. Early in tuber development the phellogen becomes active and produces the skin. During tuber maturation it becomes inactive and the skin adheres to the tuber flesh. The characterization of potato phellogen may contribute to the management of costly agricultural problems related to incomplete skin-set and the resulting skinning injuries, and provide us with new knowledge regarding cork development in planta. A transcriptome of potato tuber phellogen isolated by laser capture microdissection indicated similarity to vascular cambium and the cork from trees. Highly expressed genes and transcription factors indicated that phellogen activation involves cytokinesis and gene reprograming for the establishment of a dedifferentiation state; whereas inactivation is characterized by activity of genes that direct organ identity in meristem and cell-wall modifications. The expression of selected genes was analyzed using qPCR in native and wound periderm at distinct developmental stages. This allowed the identification of genes involved in periderm formation and maturation.
It is of note that many of the available studies of Hallyu take an ethnographic and interpretive approach and show a strong tendency to prioritize analysis of the textual content and images used in Hallyu. But there is a need to take more notice of the networks of production and dissemination, which are responsible for making Hallyu products available to fans. Indeed, understanding Hallyu networks potentially challenges long dominant Euro-American-centric accounts of production and consumption. Hence, this book is part of the attempt to build a comprehensive and interdisciplinary identity for Hallyu studies. It provides an updated account of Hallyu s traffic and acceptance in countries outside Korea s immediate neighbors, and references some of Hallyu s recent developments, notably its alignments with new media fields and with the growth of Korea s interest in cultural diplomacy.
H. Guo, Ma, C. , Thistle, L. , Huynh, M. , Yu, C. , Clasby, D. , Chefetz, Benny , Polubesova, Tamara , White, J.C. , He, L. , ו Xing, B.. 2019.
“Transformation Of Ag Ions Into Ag Nanoparticle-Loaded Agcl Microcubes In The Plant Root Zone”. Environmental Science: Nano, 6, 4, Pp. 1099-1110. doi:10.1039/c9en00088g.
Publisher's Version תקציר Natural formation of metal nanoparticles is an important pathway that will modify the fate, behavior, and biological availability of heavy metal ions in the environment. Most work has focused on the ability of natural organic matter (NOM) and extracellular polymeric substances (EPS) to convert metal ions into nanoparticles. However, plant roots, ubiquitous in soil and aquatic environments, may have a significant role in the formation of naturally occurring metal nanoparticles. This work demonstrates the importance of plant roots and associated exudates in mediating the transformation of Ag+ in the presence of sunlight. Using Ag+ as the starting material, transformation took place in three steps: 1) formation of AgCl microcubes (μAgCl) through complexation of Ag+ by plant-released chloride ions in root exudates; 2) stabilization of μAgCl by biomolecules in root exudates; 3) partial photoreduction of μAgCl to Ag(0) nanoparticles (nAg) facilitated by exudate biomolecules. Morphological and compositional changes were observed by scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDS) on the particles from 0-24 h: Cubic AgCl microcrystals were converted into cauliflower-shaped core-shell structures with nAg clusters as the shell and μAgCl as the core. The quantification of Ag+, μAgCl and nAg species over time demonstrates that the transformation kinetics fit (R2 = 0.99) a second-order reaction (k = 1.11 mM-1 h-1). The discovery of plant root exudate-mediated phototransformation of Ag+ adds new knowledge to our understanding of Ag transformation in the plant root zone and will guide the assessment of both exposure and risk in the environment. © 2019 The Royal Society of Chemistry.
Benny Chefetz, Marom, R. , Salton, O. , Oliferovsky, M. , Mordehay, V. , Ben-Ari, J. , ו Hadar, Yitzhak . 2019.
“Transformation Of Lamotrigine By White-Rot Fungus Pleurotus Ostreatus”. Environmental Pollution, 250, Pp. 546-553. doi:10.1016/j.envpol.2019.04.057.
Publisher's Version תקציר One of the most persistent pharmaceutical compounds commonly found in treated wastewater is lamotrigine (LTG). It has also been detected in soils and crops irrigated with treated wastewater. Here we focused on the ability of the white-rot edible mushroom Pleurotus ostreatus to remove and transform LTG in liquid cultures. At concentrations of environmental relevance (1 and 10 μg L−1) LTG was almost completely removed from the culture medium within 20 days. To elucidate the mechanism of LTG removal and transformation, we applied a physiological-based approach using inhibitors and a competing agent. These experiments were conducted at a higher concentration for metabolites detection. Based on identification of sulfur-containing metabolites and LTG N2-oxide and the effect of specific inhibitors, cytochrome P450 oxidation is suggested as one of the reaction mechanisms leading to LTG transformation. The variety and number of transformation products (i.e., conjugates) found in the current study were larger than reported in mammals. Moreover, known conjugates with glucuronide, glutathione, or cysteine/glycine, were not found in our system. Since the majority of the identified transformation products were conjugates of LTG, this study highlights the persistence of LTG as an organic pollutant in ecosystems exposed to wastewater. © 2019 Elsevier Ltd
Benny Chefetz, Marom, Rotem , Salton, Orit , Oliferovsky, Mariana , Mordehay, Vered , Ben-Ari, Julius , ו Hadar, Yitzhak . 2019.
“Transformation Of Lamotrigine By White-Rot Fungus Pleurotus Ostreatus”. Environmental Pollution , 250, Pp. 546 - 553. .
Publisher's Version תקציר One of the most persistent pharmaceutical compounds commonly found in treated wastewater is lamotrigine (LTG). It has also been detected in soils and crops irrigated with treated wastewater. Here we focused on the ability of the white-rot edible mushroom Pleurotus ostreatus to remove and transform LTG in liquid cultures. At concentrations of environmental relevance (1 and 10 μg L−1) LTG was almost completely removed from the culture medium within 20 days. To elucidate the mechanism of LTG removal and transformation, we applied a physiological-based approach using inhibitors and a competing agent. These experiments were conducted at a higher concentration for metabolites detection. Based on identification of sulfur-containing metabolites and LTG N2-oxide and the effect of specific inhibitors, cytochrome P450 oxidation is suggested as one of the reaction mechanisms leading to LTG transformation. The variety and number of transformation products (i.e., conjugates) found in the current study were larger than reported in mammals. Moreover, known conjugates with glucuronide, glutathione, or cysteine/glycine, were not found in our system. Since the majority of the identified transformation products were conjugates of LTG, this study highlights the persistence of LTG as an organic pollutant in ecosystems exposed to wastewater.
Eyal Maori, Garbian, Yael , Kunik, Vered , Mozes-Koch, Rita , Malka, Osnat , Kalev, Haim , Sabath, Niv , Sela, Ilan , ו Shafir, Sharoni . 2019.
“A Transmissible Rna Pathway In Honey Bees”. Cell Rep, 27, 7, Pp. 1949-1959.e6. doi:10.1016/j.celrep.2019.04.073.
תקציר Systemic RNAi, initiated by double-stranded RNA (dsRNA) ingestion, has been reported in diverse invertebrates, including honey bees, demonstrating environmental RNA uptake that undermines homologous gene expression. However, the question why any organism would take up RNA from the environment has remained largely unanswered. Here, we report on horizontal RNA flow among honey bees mediated by secretion and ingestion of worker and royal jelly diets. We demonstrate that transmission of jelly-secreted dsRNA to larvae is biologically active and triggers gene knockdown that lasts into adulthood. Worker and royal jellies harbor differential naturally occurring RNA populations. Jelly RNAs corresponded to honey bee protein-coding genes, transposable elements, and non-coding RNA, as well as bacteria, fungi, and viruses. These results reveal an inherent property of honey bees to share RNA among individuals and generations. Our findings suggest a transmissible RNA pathway, playing a role in social immunity and signaling between members of the hive.
S. Ghosh, Kanakala, S. , Lebedev, G. , Kontsedalov, S. , Silverman, D. , Alon, T. , Mor, N. , Sela, N. , Luria, N. , Dombrovsky, A. , Mawassi, M. , Haviv, S. , Czosnek, Henryk , ו Ghanim, M.. 2019.
“Transmission Of A New Polerovirus Infecting Pepper By The Whitefly Bemisia Tabaci”. Journal Of Virology, 93, 15. doi:10.1128/JVI.00488-19.
Publisher's Version תקציר Many animal and plant viruses depend on arthropods for their transmission. Virus-vector interactions are highly specific, and only one vector or one of a group of vectors from the same family is able to transmit a given virus. Poleroviruses (Luteoviridae) are phloem-restricted RNA plant viruses that are exclusively transmitted by aphids. Multiple aphid-transmitted polerovirus species commonly infect pepper, causing vein yellowing, leaf rolling, and fruit discoloration. Despite low aphid populations, a recent outbreak with such severe symptoms in many bell pepper farms in Israel led to reinvestigation of the disease and its insect vector. Here we report that this outbreak was caused by a new whitefly (Bemisia tabaci)-transmitted polerovirus, which we named Pepper whitefly-borne vein yellows virus (PeWBVYV). PeWBVYV is highly (95%) homologous to Pepper vein yellows virus (PeVYV) from Israel and Greece on its 5ʹ end half, while it is homologous to African eggplant yellows virus (AeYV) on its 3ʹ half. Koch’s postulates were proven by constructing a PeWBVYV infectious clone causing the pepper disease, which was in turn transmitted to test pepper plants by B. tabaci but not by aphids. PeWBVYV represents the first report of a whitefly-transmitted polerovirus. IMPORTANCE The high specificity of virus-vector interactions limits the possibility of a given virus changing vectors. Our report describes a new virus from a family of viruses strictly transmitted by aphids which is now transmitted by whiteflies (Bemisia tabaci) and not by aphids. This report presents the first description of polerovirus transmission by whiteflies. Whiteflies are highly resistant to insecticides and disperse over long distances, carrying virus inoculum. Thus, the report of such unusual polerovirus transmission by a supervector has extensive implications for the epidemiology of the virus disease, with ramifications concerning the international trade of agricultural commodities. © 2019 American Society for Microbiology. All Rights Reserved.
Saptarshi Ghosh, Kanakala, Surapathrudu , Lebedev, Galina , Kontsedalov, Svetlana , Silverman, David , Alon, Tamar , Mor, Neta , Sela, Noa , Luria, Neta , Dombrovsky, Aviv , Mawassi, Munir , Haviv, Sabrina , Czosnek, Henryk , ו Ghanim, Murad . 2019.
“Transmission Of A New Polerovirus Infecting Pepper By The Whitefly Bemisia Tabaci”. Journal Of Virology, 93, 15. doi:10.1128/JVI.00488-19.
Publisher's Version תקציר Many animal and plant viruses depend on arthropods for their transmission. Virus-vector interactions are highly specific, and only one vector or one of a group of vectors from the same family is able to transmit a given virus. Poleroviruses (Luteoviridae) are phloem-restricted RNA plant viruses that are exclusively transmitted by aphids. Multiple aphid-transmitted polerovirus species commonly infect pepper, causing vein yellowing, leaf rolling, and fruit discoloration. Despite low aphid populations, a recent outbreak with such severe symptoms in many bell pepper farms in Israel led to reinvestigation of the disease and its insect vector. Here we report that this outbreak was caused by a new whitefly (Bemisia tabaci)-transmitted polerovirus, which we named Pepper whitefly-borne vein yellows virus (PeWBVYV). PeWBVYV is highly (>95%) homologous to Pepper vein yellows virus (PeVYV) from Israel and Greece on its 5' end half, while it is homologous to African eggplant yellows virus (AeYV) on its 3' half. Koch’s postulates were proven by constructing a PeWBVYV infectious clone causing the pepper disease, which was in turn transmitted to test pepper plants by B. tabaci but not by aphids. PeWBVYV represents the first report of a whitefly-transmitted polerovirus.IMPORTANCE The high specificity of virus-vector interactions limits the possibility of a given virus changing vectors. Our report describes a new virus from a family of viruses strictly transmitted by aphids which is now transmitted by whiteflies (Bemisia tabaci) and not by aphids. This report presents the first description of polerovirus transmission by whiteflies. Whiteflies are highly resistant to insecticides and disperse over long distances, carrying virus inoculum. Thus, the report of such unusual polerovirus transmission by a supervector has extensive implications for the epidemiology of the virus disease, with ramifications concerning the international trade of agricultural commodities.
Michael Longley’s poetry has responded to the Northern Irish Troubles with great skill and sensitivity. This article approaches his Troubles-related work from a trauma perspective. It reads this poetry as functioning as a form of palimpsest, whereby different conflicts and wars are transposed onto one another. Longley’s relationship to his father is given special focus, as it relates Longley’s Troubles verse to the memory of World War 1 through a prism of postmemory. Other contexts are important for Longley, though, and an interpretation of “Ceasefire” concludes that Longley’s acts of multidirectional memory cannot simply be defined as instances of historical witnessing but also involve imaginative and mythical manoeuvres.
May 2019: Charles I. Armstrong is a professor of English literature at the University of Agder, in Norway. Among his publications are Reframing Yeats: Genre, Allusion and History (Bloomsbury, 2013) and the co-edited volume The Legacy of the Good Friday Agreement: Politics, Culture and Art in Northern Ireland after 1998 (Palgrave Macmillan, 2017).
Doron Kabiri, Masarwy, Razan , Schachter-Safrai, Natali , Masarwa, Reem , Hirsh Raccah, Bruria , Ezra, Yossef , ו Matok, Ilan . 2019.
“Trial Of Labor After Cesarean Delivery In Twin Gestations: Systematic Review And Meta-Analysis.”. American Journal Of Obstetrics And Gynecology, 220, 4, Pp. 336–347. doi:10.1016/j.ajog.2018.11.125.
תקציר BACKGROUND: Trial of labor after cesarean is offered as a routine option for singleton gestations with previous cesarean delivery. However, adequate data are not available to determine whether the approach is equally valid in women with twin gestation. OBJECTIVE: This systematic review and meta-analysis aimed to assess maternal morbidities associated with trial of labor after cesarean delivery in twin gestations. STUDY DESIGN: Electronic databases were searched for cohort studies and randomized controlled trials evaluating the association between trial of labor after cesarean delivery in twin gestations and pregnancy outcomes. Maternal mortality and severe morbidities, such as uterine rupture and hysterectomy, were compared between women who had trial of labor and women who had a planned repeat cesarean delivery. Pooled odds ratios were calculated using a random-effects model. Additional analyses were performed to compare trial of labor after cesarean outcomes in singleton and twin gestations. RESULTS: Eleven cohort studies including a total of 8209 twin gestations with previous cesarean delivery were included in the present study. Of these gestations, 2484 were intended for planned vaginal birth and 5725 were intended for planned repeat cesarean delivery. The rate of uterine rupture in twin gestations was higher in the trial of labor after cesarean group than the elective cesarean group (odds ratio, 10.09, 95% confidence interval, 4.30-23.69, I(2) = 68%). However, no statistically significant difference was found in the rate of uterine rupture between twin and single gestations attempting trial of labor after cesarean delivery (odds ratio, 1.34, 95% confidence interval, 0.54-3.31, I(2) = 0%). Women who attempted a trial of labor after cesarean delivery with twins did not have an increased risk of uterine scar dehiscence, hemorrhage, blood transfusion, or neonatal morbidity and mortality compared with elective repeat cesarean delivery. Patients with twins had similar rates of successful vaginal delivery as patients with singletons (odds ratio, 0.85, 95% confidence interval, 0.61-1.18, I(2) = 36%). CONCLUSION: This meta-analysis demonstrates that, although trial of labor with twins after previous cesarean delivery is associated with higher rates of uterine rupture compared with elective cesarean delivery, pregnancy outcomes and success rates are similar to a trial of labor after previous cesarean delivery in singleton gestations. Planned vaginal birth for women with twin gestation and previous cesarean delivery may be a safe alternative to a planned repeat cesarean.
D Shilo, Cohen, G, Blumenfeld, A, Goren, K, Hanhan, S, Sharon, S, Haze, A, Deutsch, D, ו Lazarovici, P. 2019.
“Tuftelin Is Required For Ngf-Induced Differentiation Of Pc12 Cells”. J Mol Neurosci, 68, 1, Pp. 135–143.
תקציר Nerve growth factor (NGF) promotes pleiotropic gene transcription-dependent biological effects, in neuronal and non-neuronal cells, including survival, proliferation, differentiation, neuroprotection, pain, and angiogenesis. It is hypothesized that during odontogenesis, NGF may be implicated in morphogenetic and mineralization events by affecting proliferation and/or differentiation of dental cells. Tuftelin belongs to the enamel associated teeth proteins and is thought to play a role in enamel mineralization. We previously reported that tuftelin transcript and protein, which are ubiquitously expressed in various tissues of embryos, adults, and tumors, were significantly upregulated during NGF-induced PC12 differentiation. To further confirm the involvement of tuftelin in the differentiation process, we established a tuftelin-knockdown neuronal PC12 cell model, using a non-cytotoxic siRNA directed towards sequences at the 3' UTR of the tuftelin gene. Using real-time PCR, we quantified tuftelin mRNA expression and found that tuftelin siRNA, but not scrambled siRNA or transfection reagents, efficiently depleted about 60% of NGF-induced tuftelin mRNA transcripts. The effect of tuftelin siRNA was quantified up to 6 days of NGF-induced differentiation. Using immunofluorescence and western blot analyses, we also found a direct correlation between reduction of 60-80% in tuftelin protein expression and inhibition of about 50-70% in NGF-induced differentiation of the cells, as was detected after 3-6 days of treatment. These results demonstrate an important role for tuftelin in NGF-induced differentiation of PC12 cells. Tuftelin could be a useful target for drug development in disease where neurotrophin therapy is required.
Stav Rahmany, Rai, Monika , Gutkin, Vitaly , Wierzbowska, Małgorzata , ו etgar, lioz . 2019.
“Tuning The Optical Properties Of Already Crystalized Hybrid Perovskite”. Solar Rrl, 2019, 1900128.
Xiaotong Li, Ke, Weijun , Traore, Boubacar , Guo, Peijun , Hadar, Ido , Kepenekian, Mikael , Even, Jacky , Katan, Claudine , Stoumpos, Constantinos C. , Schaller, Richard D. , ו Kanatzidis, Mercouri G.. 2019.
“Two-Dimensional Dion-Jacobson Hybrid Lead Iodide Perovskites With Aromatic Diammonium Cations”. Journal Of The American Chemical Society, 141, 32, Pp. 12880-12890. doi:10.1021/jacs.9b06398.
Publisher's Version תקציר Two-dimensional (2D) halide perovskites have extraordinary optoelectronic properties and structural tunability. Among them, the Dion–Jacobson phases with the inorganic layers stacking exactly on top of each other are less explored. Herein, we present the new series of 2D Dion–Jacobson halide perovskites, which adopt the general formula of A′An–1PbnI3n+1 (A′ = 4-(aminomethyl)pyridinium (4AMPY), A = methylammonium (MA), n = 1–4). By modifying the position of the CH2NH3+ group from 4AMPY to 3AMPY (3AMPY = 3-(aminomethyl)pyridinium), the stacking of the inorganic layers changes from exactly eclipsed to slightly offset. The perovskite octahedra tilts are also different between the two series, with the 3AMPY series exhibiting smaller bandgaps than the 4AMPY series. Compared to the aliphatic cation of the same size (AMP = (aminomethyl)piperidinium), the aromatic spacers increase the rigidity of the cation, reduce the interlayer spacing, and decrease the dielectric mismatch between inorganic layer and the organic spacer, showing the indirect but powerful influence of the organic cations on the structure and consequently on the optical properties of the perovskite materials. All A′An–1PbnI3n+1 compounds exhibit strong photoluminescence (PL) at room temperature. Preliminary solar cell devices based on the n = 4 perovskites as absorbers of both series exhibit promising performances, with a champion power conversion efficiency (PCE) of 9.20% for (3AMPY)(MA)3Pb4I13-based devices, which is higher than the (4AMPY)(MA)3Pb4I13 and the corresponding aliphatic analogue (3AMP)(MA)3Pb4I13-based ones.
Itay Shomroni, Youssefi, Amir , Sauerwein, Nick , Qiu, Liu , Seidler, Paul , Malz, Daniel , Nunnenkamp, Andreas , ו Kippenberg, Tobias J.. 2019.
“Two-Tone Optomechanical Instability And Its Fundamental Implications For Backaction-Evading Measurements”. Physical Review X, 9, 4, Pp. 041022. doi:10.1103/PhysRevX.9.041022.
Publisher's Version 