In the current issue of Molecular Cell, Szoradi et al. (2018) present compelling data demonstrating how the newly identified SHRED pathway in yeast selectively shifts the E3 ligase Ubr1 specificity from N-end rule substrates to misfolded proteins in cells under proteostatic stress.
Alessandro Cianchi, Anania, MP , Bisesto, F , Chiadroni, E , Curcio, A , Ferrario, M , Giribono, A , Marocchino, A , Pompili, R , Scifo, J , ו others, . 2018.
“Frontiers Of Beam Diagnostics In Plasma Accelerators: Measuring The Ultra-Fast And Ultra-Cold”. Physics Of Plasmas, 25.
S. Cohen-Goldental, Biton, I. , Zemach, H. , Many, Y. , Tonutti, P. , Kerem, Zohar , ו Ben-Ari, G.. 2018.
“Fruitlet Abscission In Olive (Olea Europaea L.)”. בתוך Acta Horticulturae, Pp. 215 - 220. International Society for Horticultural Science (ISHS), Leuven, Belgium. .
Publisher's Version We report on new material compositions enabling fully printed mechanoluminescent 3D devices by using a one-step direct write 3D printing technology. The ink is composed of PDMS, transition metal ion-doped ZnS particles, and a platinum curing retarder that enables a long open time for the printing process. 3D printed mechanoluminescent multi-material objects with complex structures were fabricated, in which light emission results from stretching or wind blowing. The multi-material printing yielded anisotropic light emission upon compression from different directions, enabling its use as a directional strain and pressure sensor. The mechanoluminescent light emission peak was tailored to match that of a perovskite material, and therefore, enabled the direct conversion of wind power in the dark into electricity, by linking the printed device to perovskite-based solar cells.
Dror Liran, Rosenberg, Itamar , West, Kenneth , Pfeiffer, Loren , ו Rapaport, Ronen . 2018.
“Fully Guided Electrically-Controlled Exciton Polaritons”. Acs Photonics, 5, Pp. 4249–4252. doi:10.1021/acsphotonics.8b00922.
Yang Zhou, Layani, Michael , Wang, Shancheng , Hu, Peng , Ke, Yujie , Magdassi, Shlomo , ו Long, Yi . 2018.
“Fully Printed Flexible Smart Hybrid Hydrogels”. Advanced Functional Materials, 28.
תקציר A printable hybrid hydrogel is fabricated by embedding poly(N-isopropylacrylamide) (PNIPAm) microparticles within a water-rich silica-alumina(Si/Al)-based gel matrix. The hybrid gel holds water content of up to 70 wt%, due to its unique Si/Al matrix. The hybrid hydrogel can respond to both heat and electrical stimuli, and can be directly printed layer-by-layer using a commercial 3-dimensional printer, without requiring any curing. The hybrid ink is printed onto a transparent, flexible conductive electrode composed of silver nanoparticles and sustains bending angles of up to 180°, which enables patterning of various flexible devices such as smart windows and a 3D optical waveguide valve.
In this paper, a new approach is recommended for damping out power system oscillations. In this approach, a new fuzzy neural proportional–integral (PI) controller (FNPIC) based static synchronous series compensator (SSSC) and a fuzzy-power system stabilizer (fuzzy-PSS) with a new structure are simultaneously employed. Adaptive learning rates based on the Lyapunov stability theory to enhance the convergence speed of the proposed controller are obtained. In the structure of fuzzy-PSS, a pattern search algorithm is used to adjust four gains. A two-area four-machine power system and a three-area, three-machine power system are employed to investigate the efficiency of the proposed method. Simulations results confirm the capabilities of proposed controller in suppressing the power system oscillations.
Miriam G. Shtriker, Peri, Irena , Taieb, Elise , Nyska, Abraham , Tirosh, Oren , ו Madar, Zecharia . 2018.
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Galactomannan More Than Pectin Exacerbates Liver Injury In Mice Fed With High‐Fat, High‐Cholesterol Diet
”. Molecular Nurtition And Food Research. .
Publisher's Version Miriam G. Shtriker, Peri, Irena , Taieb, Elise , Nyska, Abraham , Tirosh, Oren , ו Madar, Zecharia . 2018.
“Galactomannan More Than Pectin Exacerbates Liver Injury In Mice Fed With High-Fat, High-Cholesterol Diet”. Molecular Nutrition & Food Research, 62, 20, Pp. 1800331. .
Publisher's Version תקציר Scope Galactomannan and citrus pectin are considered ?super fibers? known for altering gut microbiota composition and improving glucose and lipid metabolism. The study aims to investigate the fiber's effect on a nonalcoholic steatohepatitis (NASH) model. Methods and results Two feeding experiments are carried out using groups of 7?8 week-old male C57BL/6J mice. The diets used are based on a high cholesterol/cholate diet (HCD), such as a nutritional NASH model. Mice are fed a diet with or without 15% fiber-citrus pectin (HCD-CP) or galactomannan (HCD-G) together with the HCD (first experiment), which commenced 3 weeks prior to the HCD (second experiment). Liver damage is evaluated by histological and biochemical parameters. Galactomannan leads to lesser weight gain and improved glucose tolerance, but increased liver damage. This is shown by elevated levels of liver enzymes compared to that with HCD alone. Fibers induce higher steatosis, as evaluated by liver histology. This intriguing result is linked to various changes in the gut microbiota, such as elevated Proteobacteria levels in the galactomannan group, which are correlated with disturbed metabolism and dysbiosis. Conclusions In a NASH mouse model, galactomannan increases liver damage but improves glucose metabolism. Changes in the microbiota composition may answer this enigmatic observation.
A game of threats on a finite set of players, N, is a function d that assigns a real number to any coalition, S⊆N, such that d(S)=-d(N\S). A game of threats is not necessarily a coalitional game as it may fail to satisfy the condition d(∅)=0. We show that analogs of the classic Shapley axioms for coalitional games determine a unique value for games of threats. This value assigns to each player an average of d(S) across all the coalitions that include the player. Games of threats arise naturally in value theory for strategic games, and may have applications in other branches of game theory.
Recently, gem-diborylalkanes have attracted much attention as versatile building blocks and fundamental intermediates in organic synthesis, because they enable multiple C–C bond construction and further transformation at C–B bonds. Importantly, gem-diborylalkanes can be utilised as bisnucleophilic partners in a variety of chemo-selective C–C bond-forming reactions. This review describes recent developments in synthesising gem-diborylalkanes in complex molecules along with their chemical transformation. In the first part of the review the different synthetic approaches used to synthesise gem-diborylalkanes are described. In the second part, an overview of the chemoselective transformation of gem-diborylalkanes into various functionalized materials is discussed along with one-carbon homologation of diborylmethane via a selective uni- and bidirectional method.