2021
V. Shumeiko, Malach, E. , Helman, Y. , Paltiel, Y. , Bisker, G. , Hayouka, Z. , ו Shoseyov, O.. 2021.
“A Nanoscale Optical Biosensor Based On Peptide Encapsulated Swcnts For Detection Of Acetic Acid In The Gaseous Phase”. Sensors And Actuators, B: Chemical, 327. doi:10.1016/j.snb.2020.128832.
Publisher's Version Biosensors play a key role in almost every field of human activity – ranging from biomedical diagnosis and point-of-care health monitoring to environmental monitoring and forensics. Single-walled carbon nanotubes (SWCNTs) are one of the most promising materials for near-infrared (NIR) fluorescence-based biosensing. Herein, we develop a reusable, drop-casted, real-time optical biosensor based on peptide-encapsulated SWCNTs for the detection of low concentrations of acetic acid in the air, at room temperature. While detection of NIR signal usually requires expensive and bulky equipment, here we use the (6,5) SWCNTs chirality whose peak fluorescence lies within the range of 970 nm – 1050 nm, enabling the usage of low cost and compact silicon-based detectors. We demonstrate the detection of wine spoilage based on excess gaseous acetic acid using peptide-wrapped SWCNT sensors down to 0.05% (v/v) acetic acid concentrations. Our results open new avenues for gas phase detection using NIR fluorescent SWCNT nanosensors. © 2020 Elsevier B.V.
Vlad Shumeiko, Paltiel, Yossi , Bisker, Gili , Hayouka, Zvi , ו Shoseyov, Oded . 2021.
“A Nanoscale Paper-Based Near-Infrared Optical Nose (Niron)”. Biosensors And Bioelectronics, 172, Pp. 112763. doi:https://doi.org/10.1016/j.bios.2020.112763.
Publisher's Version תקציר Electronic noses (e-nose) and optical noses (o-nose) are two emerging approaches for the development of artificial olfactory systems for flavor and smell evaluation. The current work leverages the unique optical properties of semiconducting single-wall carbon nanotubes (SWCNTs) to develop a prototype of a novel paper-based near-infrared optical nose (NIRON). We have drop-dried an array of SWCNTs encapsulated with a wide variety of peptides on a paper substrate and continuously imaged the emitted SWCNTs fluorescence using a CMOS camera. Odors and different volatile molecules were passed above the array in a flow chamber, resulting in unique modulation patterns of the SWCNT photoluminescence (PL). Quartz crystal microbalance (QCM) measurements performed in parallel confirmed the direct binding between the vapor molecules and the peptide-SWCNTs. PL levels measured before and during exposure demonstrate distinct responses to the four tested alcoholic vapors (ethanol, methanol, propanol, and isopropanol). In addition, machine learning tools directly applied to the fluorescence images allow us to distinguish between the aromas of red wine, beer, and vodka. Further, we show that the developed sensor can detect limonene, undecanal, and geraniol vapors, and differentiate between their smells utilizing the PL response pattern. This novel paper-based optical biosensor provides data in real-time, and is recoverable and suitable for working at room temperature and in a wide range of humidity levels. This platform opens new avenues for real-time sensing of volatile chemical compounds, odors, and flavors.
Vlad Shumeiko, Paltiel, Yossi , Bisker, Gili , Hayouka, Zvi , ו Shoseyov, Oded . 2021.
“A Nanoscale Paper-Based Near-Infrared Optical Nose (Niron)”. Biosensors And Bioelectronics, 172, Pp. 112763. doi:https://doi.org/10.1016/j.bios.2020.112763.
Publisher's Version תקציר Electronic noses (e-nose) and optical noses (o-nose) are two emerging approaches for the development of artificial olfactory systems for flavor and smell evaluation. The current work leverages the unique optical properties of semiconducting single-wall carbon nanotubes (SWCNTs) to develop a prototype of a novel paper-based near-infrared optical nose (NIRON). We have drop-dried an array of SWCNTs encapsulated with a wide variety of peptides on a paper substrate and continuously imaged the emitted SWCNTs fluorescence using a CMOS camera. Odors and different volatile molecules were passed above the array in a flow chamber, resulting in unique modulation patterns of the SWCNT photoluminescence (PL). Quartz crystal microbalance (QCM) measurements performed in parallel confirmed the direct binding between the vapor molecules and the peptide-SWCNTs. PL levels measured before and during exposure demonstrate distinct responses to the four tested alcoholic vapors (ethanol, methanol, propanol, and isopropanol). In addition, machine learning tools directly applied to the fluorescence images allow us to distinguish between the aromas of red wine, beer, and vodka. Further, we show that the developed sensor can detect limonene, undecanal, and geraniol vapors, and differentiate between their smells utilizing the PL response pattern. This novel paper-based optical biosensor provides data in real-time, and is recoverable and suitable for working at room temperature and in a wide range of humidity levels. This platform opens new avenues for real-time sensing of volatile chemical compounds, odors, and flavors.
Electronic noses (e-nose) and optical noses (o-nose) are two emerging approaches for the development of artificial olfactory systems for flavor and smell evaluation. The current work leverages the unique optical properties of semiconducting single-wall carbon nanotubes (SWCNTs) to develop a prototype of a novel paper-based near-infrared optical nose (NIRON). We have drop-dried an array of SWCNTs encapsulated with a wide variety of peptides on a paper substrate and continuously imaged the emitted SWCNTs fluorescence using a CMOS camera. Odors and different volatile molecules were passed above the array in a flow chamber, resulting in unique modulation patterns of the SWCNT photoluminescence (PL). Quartz crystal microbalance (QCM) measurements performed in parallel confirmed the direct binding between the vapor molecules and the peptide-SWCNTs. PL levels measured before and during exposure demonstrate distinct responses to the four tested alcoholic vapors (ethanol, methanol, propanol, and isopropanol). In addition, machine learning tools directly applied to the fluorescence images allow us to distinguish between the aromas of red wine, beer, and vodka. Further, we show that the developed sensor can detect limonene, undecanal, and geraniol vapors, and differentiate between their smells utilizing the PL response pattern. This novel paper-based optical biosensor provides data in real-time, and is recoverable and suitable for working at room temperature and in a wide range of humidity levels. This platform opens new avenues for real-time sensing of volatile chemical compounds, odors, and flavors. © 2020 Elsevier B.V.
The book tells the geopolitical anatomy of the Second World War. An unfamiliar perspective is taken: the narrator looks substantially from south to north, in a subordinate way from west to east. Nevertheless, both horizons are merged into one another, focusing on different forms of violence executed during warfare and beyond, while trying to judge their bearings and repercussions in material reality as well as in public memory. Jewish Palestine, situated at the intersection of European-continental and non-European colonial perception, serves as an insightful hub of understanding and meaning for such an epistemological fusion. Its geographical location at the extreme north-western tip of imperial British rule in Asia always calls India as a reference to the overall spatial narrative that finds its core period in 1935/1942 – between the Italian "Abyssinia War" and the fateful battles of El-Alamain and Stalingrad.
This study aims to determine how feelings of nationalism or patriotism for one's own country and feelings of animosity for countries that are in political conflict affect consumers’ willingness to refrain from buying products from various origins. Four hundred forty-two shoppers participated in a survey that included questions about ethnocentric and patriotic feelings and a choice task between local and foreign produce. We find that a significant proportion of Israeli consumers are not willing to buy imported produce from countries that are in conflict with Israel. The proportion of consumers who would not purchase imported produce increases substantially with the intensity of the conflict. Consumers who avoid buying produce from friendly countries are those whose ethnocentric and economic-centric relationship are strong.
Laia Castro, Strömbäck, Jesper , Esser, Frank , van Aelst, Peter , de Vreese, Claes , Aalberg, Toril , Cardenal, Ana S. , Corbu, Nicoleta , Hopmann, David Nicolas , Koc-Michalska1, Karolina , Matthes, Jörg , Schemer, Christian , Sheafer, Tamir , Splendore1, Sergio , Stanyer, James , Ste˛pin´ska, Agnieszka , Šteˇtka, Václav , ו Theocharis, Yannis . 2021.
“Navigating High-Choice European Political Information Environments: A Comparative Analysis Of News User Profiles And Political Knowledge”. The International Journal Of Press/Politics.
DOI: 10.1177/19401612211012572.
Publisher's Version Ronn Goei, Ong, Amanda Jiamin, Tan, Jun Hao, Loke, Jie Yi, Lua, Shun Kuang, Mandler, Daniel , Magdassi, Shlomo , ו Tok, Alfred Iing Yoong. 2021.
“Nd-Nb Co-Doped Sno2/Alpha-Wo3 Electrochromic Materials: Enhanced Stability And Switching Properties”. Acs Omega, 6, Pp. 26251-26261. doi:10.1021/acsomega.1c03260.
Ronn Goei, Ong, Amanda Jiamin, Tan, Jun Hao, Loke, Jie Yi, Lua, Shun Kuang, Mandler, Daniel , Magdassi, Shlomo , ו Tok, Alfred Iing Yoong. 2021.
“Nd-Nb Co-Doped Sno2/Α-Wo3Electrochromic Materials: Enhanced Stability And Switching Properties”. Acs Omega, 6, Pp. 26251–26261.
תקציר The fabrication of Nd-Nb co-doped SnO2/α-WO3 electrochromic (EC) materials for smart window applications is presented in the present paper. Nb is a good dopant candidate for ECs owing to its ability to introduce active sites on the surface of α-WO3 without causing much lattice strain due to the similar ionic radius of Nb5+ and W6+. These active sites introduce more channels for charge insertion or removal during redox reactions, improving the overall EC performance. However, Nb suffers from prolonged utilization due to the Li+ ions trapped within the ECs. By coupling Nd with Nb, the co-dopants would transfer their excess electrons to SnO2, improving the electronic conductivity and easing the insertion and extraction of Li+ cations from the ECs. The enhanced Nd-Nb co-doped SnO2/α-WO3 exhibited excellent visible light transmission (90% transmittance), high near-infrared (NIR) contrast (60% NIR modulation), rapid switching time (∼1 s), and excellent stability (>65% of NIR modulation was retained after repeated electrochemical cycles). The mechanism of enhanced EC performance was also investigated. The novel combination of Nd-Nb co-doped SnO2/α-WO3 presented in this work demonstrates an excellent candidate material for smart window applications to be used in green buildings.
Jiabin Cui, Koley, Somnath , Panfil, Yossef E. , Levi, Adar , Ossia, Yonatan , Waiskopf, Nir , Remennik, Sergei , Oded, Meirav , ו Banin, Uri . 11/2021.
“Neck Barrier Engineering In Quantum Dot Dimer Molecules Via Intraparticle Ripening”. Journal Of The American Chemical Society, 143, 47, Pp. 19816–19823. .
Publisher's Version תקציר Coupled colloidal quantum dot (CQD) dimers represent a new class of artificial molecules composed of fused core/shell semiconductor nanocrystals. The electronic coupling and wave function hybridization are enabled by the formation of an epitaxial connection with a coherent lattice between the shells of the two neighboring quantum dots where the shell material and its dimensions dictate the quantum barrier characteristics for the charge carriers.
Herein we introduce a colloidal approach to control the neck formation at the interface between the two CQDs in such artificial molecular constructs. This allows the tailoring of the neck barrier in prelinked homodimers formed via fusion of multifaceted wurtzite CdSe/CdS CQDs. The effects of reaction time, temperature, and excess ligands are studied. The neck filling process follows an intraparticle ripening mechanism at relatively mild reaction conditions while avoiding interparticle ripening. The degree of surface ligand passivation plays a key role in activating the surface atom diffusion to the neck region. The degree of neck filling strongly depends also on the initial relative orientation of the two CQDs, where homonymous plane attachment allows for facile neck growth, unlike the case of heteronymous plane attachment. Upon neck filling, the observed red-shift of the absorption and fluorescence measured both for ensemble and single dimers is assigned to enhanced hybridization of the confined wave function in CQD dimer molecules, as supported by quantum calculations. The fine-tuning of the particle interface introduced herein provides therefore a powerful tool to further control the extent of hybridization and coupling in CQD molecules.Coupled colloidal quantum dot (CQD) dimers represent a new class of artificial molecules composed of fused core/shell semiconductor nanocrystals. The electronic coupling and wave function hybridization are enabled by the formation of an epitaxial connection with a coherent lattice between the shells of the two neighboring quantum dots where the shell material and its dimensions dictate the quantum barrier characteristics for the charge carriers. Herein we introduce a colloidal approach to control the neck formation at the interface between the two CQDs in such artificial molecular constructs. This allows the tailoring of the neck barrier in prelinked homodimers formed via fusion of multifaceted wurtzite CdSe/CdS CQDs. The effects of reaction time, temperature, and excess ligands are studied. The neck filling process follows an intraparticle ripening mechanism at relatively mild reaction conditions while avoiding interparticle ripening. The degree of surface ligand passivation plays a key role in activating the surface atom diffusion to the neck region. The degree of neck filling strongly depends also on the initial relative orientation of the two CQDs, where homonymous plane attachment allows for facile neck growth, unlike the case of heteronymous plane attachment. Upon neck filling, the observed red-shift of the absorption and fluorescence measured both for ensemble and single dimers is assigned to enhanced hybridization of the confined wave function in CQD dimer molecules, as supported by quantum calculations. The fine-tuning of the particle interface introduced herein provides therefore a powerful tool to further control the extent of hybridization and coupling in CQD molecules.
Anat Talmon, Dixon, Matthew Luke , Goldin, Philippe R, Heimberg, Richard G, ו Gross, James J. 2021.
“Neurocognitive Heterogeneity In Social Anxiety Disorder: The Role Of Self-Referential Processing And Childhood Maltreatment”. Clinical Psychological Science, 9, Pp. 1045–1058.
Andrea Barp, Lizio, Andrea , Gerardi, Francesca , Tarlarini, Claudia , Mauro, Luca , Sansone, Valeria Ada , ו Lunetta, Christian . 2021.
“Neurophysiological Indices In Amyotrophic Lateral Sclerosis Correlate With Functional Outcome Measures, Staging And Disease Progression”. Clin. Neurophysiol., 132, 7, Pp. 1564–1571.
תקציר OBJECTIVE: This study examined neurophysiological (NI), split-hand (SI) and split-leg (SLI) index in patients with amyotrophic lateral sclerosis (ALS), and their correlation with functional status, disease duration, staging and survival. METHODS: Eighty-two patients underwent nerve conduction study to analyze NI, SI and SLI. Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R), disease progression rate ($Δ$FS), Milano-Torino (MiToS) and King's staging systems, Forced Vital Capacity (FVC), and survival data were collected. RESULTS: Both NI and SI indices were significantly associated with ALSFRS-R, MiToS, King's and FVC. Slow progressor patients ($Δ$FS < 0.5) reported a significantly higher NI and SI values compared to both normal (0.5 $łeq$ $Δ$FS < 1.00) and fast progressors ($Δ$FS $\geq$ 1.0). After dichotomizing patients in slow progressors ($Δ$FS < 0.5) and not-slow progressors ($Δ$FS $\geq$ 0.5), a combination of SI index and disease duration revealed to be the best prediction model to discriminate patients in accordance with their disease progression (c-index: 0.92), leading to a new prognostic index: the 'Split-Hand prognostic index' (SHpi). CONCLUSION: SI and NI are correlated with functional status and FVC. SHpi index could represent an useful tool to discriminate patients in accordance with their disease progression. SIGNIFICANCE: These data provide novel evidence of neurophysiological indices as promising biomarkers in ALS.
Limor Rubin, Stabler, Collin T. , Schumacher-Klinger, Adi , Marcinkiewicz, Cezary , Lelkes, Peter I. , ו Lazarovici, Philip . 2021.
“Neurotrophic Factors And Their Receptors In Lung Development And Implications In Lung Diseases”. Cytokine And Growth Factor Reviews, 59, Pp. 84–94. doi:10.1016/J.CYTOGFR.2021.01.008.
תקציר Although lung innervation has been described by many studies in humans and rodents, the regulation of the respiratory system induced by neurotrophins is not fully understood. Here, we review current knowledge on the role of neurotrophins and the expression and function of their receptors in neurogenesis, vasculogenesis and during the embryonic development of the respiratory tree and highlight key implications relevant to respiratory diseases.
