Shamrakov, D., Levi-Kalisman, Y., Nudelman, S., Peretz-Damari, S., Nativ-Roth, E., Regev, O. and Barenholz, Y., Quantitative Cryo-TEM Reveals New Structural Details of Doxil-Like PEGylated Liposomal Doxorubicin Formulation. Pharmaceutics 13(1), 123 (2021). https://doi.org/10.3390/pharmaceutics13010123
Bavli, Y., Rabie, M., Fellig, Y., Nevo, Y. and Barenholz, Y., Liposomal Bupivacaine (Bupigel) Demonstrates Minimal Local Nerve Toxicity in a Rabbit Functional Model. Pharmaceutics 13, 185 (2021). https://doi.org/10.3390/pharmaceutics13020185
Golstein, Y., Spitz, S., Turjeman, K., Selinger, F., Barenholz, Y., Ertl, P., Benny, O. and Bavli, D., Breaking the Third Wall: Implementing 3D Printing Technics to Expand the Complexity and Abilities of Multi-Organ-on-a-Chip Devices. Micromachines 12, 627 (2021). https://doi.org/10.3390/mi12060627
Grabarnick, E., Andriyanov, A.V., Han, H., Eyal, S. and Barenholz, Y., PEGylated Liposomes Remotely Loaded with the Combination of Doxorubicin. Pharmaceutics 13, 2181 (2021). https://doi.org/10.3390/pharmaceutics13122181
Cern, A., Bavli, Y., Hod, A., Zilbersheid, D., Mushtaq, S., Michael-Gayego, A., Barasch, D., Feinstein Rotkopf, Y., Moses, A.E., Livermore, D.M. and Barenholz, Y., Therapeutic Potential of Injectable NanoMupirocin Liposomes for Infections Involving Multidrug-Resistant Bacteria. Pharmaceutics 13, 2186 (2021). https://doi.org/10.3390/pharmaceutics13122186
Szebeni, J., Storm, G., Ljubimova, J.Y., Castells, M., Phillips, E.J., Turjeman, K., Barenholz, Y., Dobrovolskaia, M.A. and Crommelin, D.J.A., Applying lessons learned from nanomedicines to understand rare hypersensitivity reactions to mRNA-based SARS-coV2 vaccines. Nature Nanotechnology (2022).
Saragovi, A., Zilberman, T., Yasur, G., Turjeman, K., Abramovich, I., Kuchersky, M., Gottlieb, E., Barenholz, Y. and Berger, M., Analysis of cellular water content in T cells reveals a switch from slow metabolic water gain to rapid water influx prior to cell division. Journal of Biological Chemistry 298(4), 101795 (2022). https://doi.org/10.1016/j.jbc.2022.101795
Shilo-Benjamini, Y., Cern, A., Zilbersheid, D., Hod, A., Lavy, E., Barasch, D. and Barenholz, Y., A Case Report of Subcutaneously Injected Liposomal Cannabidiol Formulation Used as a Compassion Therapy for Pain Management in a Dog. Frontiers in Veterinary Science 9, 892306 (2022). https://doi.org/10.3389/fvets.2022.892306
Bavli, Y., Chen, B.M., Gross, G., Hershko, A., Turjeman, K., Roffler, S. and Barenholz, Y., Anti-PEG antibodies before and after a first dose of Comirnaty® (mRNA-LNP-based SARS-CoV-2 vaccine). Journal of Controlled Release 354, 316–322 (2023).
Pinto, N., Klein, Y., David, E., Polak, D., Steinberg, D., Mizrahi, G., Khoury, Y., Barenholz, Y. and Chaushu, S., Resolvin D1 improves allograft osteointegration and directly enhances osteoblasts differentiation. Frontiers in Immunology 14, 1086930 (2023). https://doi.org/10.3389/fimmu.2023.1086930
Szebeni, J., Kiss, B., Bozó, T., Turjeman, K., Levi-Kalisman, Y., Barenholz, Y. and Kellermayer, M., Insights into the Structure of Comirnaty Covid-19 Vaccine: A Theory on Soft, Partially Bilayer-Covered Nanoparticles with Hydrogen Bond-Stabilized mRNA–Lipid Complexes. ACS Nano 17(14), 13147–13157 (2023). https://doi.org/10.1021/acsnano.2c11904
Shilo-Benjamini, Y., Lavy, E., Yair, N., Milgram, J., Zilbersheid, D., Hod, A., Barasch, D., Abu Ahmad, W., Cern, A. and Barenholz, Y., Therapeutic efficacy and pharmacokinetics of liposomal cannabidiol injection: a pilot clinical study in dogs with naturally occurring osteoarthritis. Frontiers in Veterinary Science 10, 1224452 (2023). https://doi.org/10.3389/fvets.2023.1224452
Chen, W.A., Chang, D.Y., Chen, B.M., Lin, Y.C., Barenholz, Y. and Roffler, S.R., Antibodies against Poly(ethylene glycol) Activate Innate Immune Cells and Induce Hypersensitivity Reactions to PEGylated Nanomedicines. ACS Nano 17(6), 5757–5772 (2023). https://doi.org/10.1021/acsnano.2c12193
Schnitzer, T.J., Rovsing, H., Lau, E., Boll, S.L., Brahmachari, B. and Chou, R.C., Intra-articular MM-II, a novel suspension of large empty multilamellar liposomes, in painful knee osteoarthritis: a 26-week phase 2b placebo-controlled double blind randomized trial. Osteoarthritis and Cartilage 31, 688–689 (2023). (Barenholz is not a coauthor)
Anchordoquy, T., Artzi, N., Balyasnikova, I.V., Barenholz, Y., La-Beck, N.M., Brenner, J.S., Chan, W.C.W., Decuzzi, P., Exner, A.A., Gabizon, A., Godin, B., Lai, S.K., Lammers, T., Mitchell, M.J., Moghimi, S.M., Muzykantov, V.R., Peer, D., Nguyen, J., Popovtzer, R., Ricco, M., Serkova, N.J., Singh, R., Schroeder, A., Schwendeman, A.A., Straehla, J.P., Teesalu, T., Tilden, S. and Simberg, D., Mechanisms and Barriers in Nanomedicine: Progress in the Field and Future Directions. ACS Nano 18, 13983–13999 (2024). https://doi.org/10.1021/acsnano.4c00182
Cern, A., Skoczen, S.L., Snapp, K.S., Hod, A., Zilbersheid, D., Bavli, Y., Alon-Maimon, T., Bachrach, G., Wei, X., Berman, B., Yassour, M., Cedrone, E., Neun, B.W., Dobrovolskaia, M.A., Clogston, J.D., Stern, S.T. and Barenholz, Y., Nano-mupirocin as tumor-targeted antibiotic: Physicochemical, immunotoxicological and pharmacokinetic characterization, and effect on gut microbiome. Journal of Controlled Release 373, 713–726 (2024). https://doi.org/10.1016/j.jconrel.2024.07.045
Chen, B.M., Even-Chen, S., Lin, Y.C., Thi My Tran, T., Turjeman, K., Yang, C.H., Cheng, T.L., Barenholz, Y. and Roffler, S.R., Liposomes with Low Levels of Grafted Poly(ethylene glycol) Remain Susceptible to Destabilization by Anti-Poly(ethylene glycol) Antibodies. ACS Nano 18(33), 22122–22138 (2024). https://doi.org/10.1021/acsnano.4c05409
Wechsler, R., Bendele, A., Pinkus, R., Sarfati, G., Rotem, R., Kasem, H., Turjeman, K. and Barenholz, Y., Empty large liposomes reduce cartilage degeneration in osteoarthritic rats by forming a lubricative coating. Osteoarthritis and Cartilage 33(7), 848–860 (2025). https://doi.org/10.1016/j.joca.2025.02.774
Simberg, D., Barenholz, Y., Roffler, S.R., Landfester, K., Kabanov, A.V. and Moghimi, S.M., PEGylation technology: addressing concerns, moving forward. Drug Delivery 32(1), 2494775 (2025). https://doi.org/10.1080/10717544.2025.2494775
Turjeman, K., Egler-Kemmerer, A.N., Shamrakov, D., Paulus, C., Thiermann, R., Barenholz, Y. and Bleul, R., Comparing continuous micromixing and extrusion downsizing for PEGylated nanoliposomes remotely loaded with doxorubicin or the steroid pro-drug methylprednisolone hemisuccinate. Journal of Controlled Release 382, 113707 (2025). https://doi.org/10.1016/j.jconrel.2025.113707
Kalo, E., Nelson, K., Shilo-Benjamini, Y., Wajnerman, A., Vasilevski, N., Hifi, O., Barasch, D., Rozenberg-Hasson, P., Cern, A. and Barenholz, Y., Liposomal-Cannabidiol Injection; Preliminary Insights into Pharmacokinetics and Safety Characteristics in Göttingen Minipigs and Rabbits. Precision Nanomedicine 8(3), 1525–1541 (2025). https://doi.org/10.33218/001c.141764
Crist, R.M., Barenholz, Y., Cern, A., Clark, K.N., Cullis, P.R., Dean, C., Desai, N., Ferrari, M., Germain, M., Giacomantonio, C.A., Grabarnik, E., Grodzinski, P., Hod, A., Kennedy, B.E., Kularatne, R.N., Kwon, G.S., Loeb, E., Noftall, E.B., Pagliaro, L., Rasoulianboroujeni, M. et al., Advancing Medical Applications of Cancer Nanotechnology: Highlighting Two Decades of the NCI's Nanotechnology Characterization Laboratory Service to the Research Community. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 17(3), e70020 (2025).
Shilo-Benjamini, Y., Abu Ahmad, W., Barasch, D., Lavy, E., Zilbersheid, D., Barenholz, Y. and Cern, A., Liposomal-synthetic-cannabidiol: preliminary translational evidence of efficacy, tolerability and pharmacokinetics following repeated subcutaneous injections in two goats. Frontiers in Pharmacology 16, 1689226 (2025).
Shilo-Benjamini, Y., Milgram, J., Lavy, E., Quint, M., Barasch, D., Cern, A. and Barenholz, Y., Efficacy, pharmacokinetics and safety of liposomal synthetic cannabidiol injected subcutaneously in dogs: a randomized, blinded, placebo-controlled, crossover clinical trial. Frontiers in Veterinary Science 12, 1746266 (2026).
Shilo-Benjamini, Y., dos Santos Silva, P., Cern, A., Aroch, I., Abu Ahmad, W., Barasch, D., Lavy, E., Barenholz, Y. and Zachut, M., Pharmacokinetics and tolerability of liposomal synthetic cannabidiol subcutaneous depot in Holstein dairy calves. Journal of Dairy Science 109(2), 1936–1950 (2026).