Amselem, S., Cohen, R., Druckmann, S., Gabizon, A., Goren, D., Abra, R.M., Huang, A., New, R. and Barenholz, Y., Preparation and characterization of liposomal doxorubicin for human use. J. Liposome Res. 2, 93–123 (1992).

Barenholz, Y., Liposome production: Historic aspects. In: Liposome Dermatics (BraunFalco, O., Korting, H.C. and Maibach, H.I., eds.), Springer Verlag, Berlin, pp. 69–81 (1992).

Goetschel, R., Barenholz, Y. and Bar, R., Microbial conversions in a liposomal medium part: Cholesterol oxidation by Rhodococcus erythropolis. Enzyme Microb. Technol. 14, 390–395 (1992).

Kalmanzon, E., Zlotkin, E., Cohen, R. and Barenholz, Y., Liposomes as a model for the study of the mechanism of fish toxicity of sodium dodecyl sulfate in sea water. Biochim. Biophys. Acta 1103, 148–156 (1992).

Barenholz, Y. and Gabizon, A., Liposomes in cancer chemotherapy: experimental strategies. In: Trends in Medicinal Chemistry 90 (Agranat, I. and Meshulam, R., eds.), Blackwell Scientific Publications, Oxford, pp. 393–395 (1992).

Lasic, D.D., Frederik, P.M., Stuart, M.C.A., Barenholz, Y. and McIntosh, T.J., Gelation of liposome interior. A novel method for drug encapsulation. FEBS Lett. 312, 255–258 (1992).

Horowitz, A.T., Barenholz, Y. and Gabizon, A.A., In vitro cytotoxicity of liposomeencapsulated doxorubicin: dependence on liposome composition and drug release. Biochim. Biophys. Acta 1109, 203–209 (1992).

Amselem, S., Gabizon, A. and Barenholz, Y., A large-scale method for the preparation of sterile and nonpyrogenic liposomal formulations of defined size distributions for clinical use. In: Liposome Technology, 2nd Edition, Vol. I, Liposome Preparation and Related Techniques. (Gregoriadis, G., ed.), CRC Press, Boca Raton, FL, pp. 501–525 (1993).

Barenholz, Y. and Amselem, S., Quality control assays in the development and clinical use of liposomebased formulations. In: Liposome Technology, 2nd Edition, Vol. I, Liposome Preparation and Related Techniques. (Gregoriadis, G., ed.), CRC Press, Boca Raton, FL, pp. 527–616 (1993).

Storm, G., Oussoren, C., Peeters, P.A.M. and Barenholz, Y., Tolerability of liposomes in vivo. In: Liposome Technology, 2nd Edition, Vol. III, Interactions of Liposomes with the Biological Milieu. Gregoriadis, G., ed.), CRC Press, BocaRaton, FL, pp. 345–383 (1993).

Barenholz, Y., Amselem, S., Goren, D., Cohen, R., Gelvan, D., Samuni, A., Golden, E.B. and Gabizon, A., Stability of liposomaldoxorubicin formulation: problems and prospects. Med. Res. Rev. 13, 449–491 (1993).

Gabizon, A.A., Barenholz, Y. and Bialer, M., Prolongation of the circulation time of doxorubicin encapsulated in liposomes containing a polyethylene glycolderivatized phospholipid: Pharmacokinetic studies in rodents and dogs. Pharmaceutical Res. 10, 703–708 (1993).

Levy, M.Y., Polacheck, I., Barenholz, Y. and Benita, S., Efficacy evaluation of a novel submicron amphotericin B emulsion in murine candidiasis. J. Med. Vet. Mycol. 31, 207–218 (1993).

Engelhard, D., Eldor, A., Polacheck, I., Hardan, I., Ben Yehuda, D., Amselem, S., Solkin, I.F., LopezBerestein, G., Sacks, I., Rachmilewitz, E. and Barenholz, Y., Disseminated visceral fusariosis cured by Amphotericin B lipid complex. Leukemia and Lymphoma 9, 385–392 (1993).

Diminsky, D., EvenChen, Z. and Barenholz, Y., Preparation and characterization of stable liposomal Hepatitis B vaccine. In: New Generation Vaccines: The Role of Basic Immunology. (Gregoriadis, G., Allison, A.C. and Poste, G., eds.), NATO ASI Series, Plenum, NY, pp. 51–59 (1993).

Barenholz, Y., Palgi, O., Golod, G., Emanuel, N., Rutkoski, Y., Braun, E. and Kedar, E., Liposomal delivery of cytokines: a means to improve their therapeutic performance. In: New Generation Vaccines: The Role of Basic Immunology. (Gregoriadis, G., Allison, A.C. and Poste, G., eds.), NATO ASI Series, Plenum, NY, pp. 201–210 (1993).

Bach, D., Miller, I.R. and Barenholz, Y., Thermotropic behavior of phosphatidylcholineglucosyl ceramide mixtures: Effects of phospholipid acyl chain composition and interaction with water. Biophys. Chem. 47, 77–86 (1993).

Borenstain, V., Barenholz, Y., HyAm, E., Rachmilewitz, E.A. and Eldor, A., Phosphatidylserine in the outer leaflet of red blood cells from ßthalassemia patients may explain the chronic hypercoagulable state and thrombotic episodes. Am. J. Hematol. 44, 63–65 (1993).

Haran, G., Cohen, R., Bar, L.K. and Barenholz, Y., Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim. Biophys. Acta 1151, 201–215 (1993).

Gorodetsky, R., Amselem, S. and Barenholz, Y., Trace element analysis of liposomal formulations by diagnostic Xray fluorescence spectrometry (DXS). Chem. Phys. Lipids 64, 31–34 (1993).

Borenstain, V. and Barenholz, Y., Characterization of liposomes and other lipid assemblies by multiprobe fluorescence polarization. Chem. Phys. Lipids 64, 117–127 (1993).

Amselem, S., Cohen, R. and Barenholz, Y., In vitro tests to predict in vivo performance of liposomal dosage forms. Chem. Phys. Lipids 64, 219–237 (1993).

Barenholz, Y., Pal, R. and Wagner, R.R., Metabolic labelling of viral membrane lipids by fluorescent fatty acids: Studying virus fusion with target membranes. In: Membrane Fusion Techniques. Methods Enzymol. 220, 288–312 (1993).

Gregoriadis, G., Wang, Z., Barenholz, Y. and Francis, M.J., Liposome-entrapped Tcell peptide provides help for a co-entrapped Bcell peptide to overcome genetic restriction in mice and induce immunological memory. Immunology 80, 535–540 (1993).

A Eldor, J Maclouf, F Lellouche, V Ben-Yashar, Y Barenholz, R Durst, E Hy-Am, A Goldfarb, E Rachmilewitz A chronic hypercoagulable state and life-long platelet activation in beta thalassemia major. The Southeast Asian journal of tropical medicine and public health, 24, 92–95 (1993)

Barenholz, Y. and Crommelin, D.J.A., Liposomes as pharmaceutical dosage forms. In: Encyclopedia of Pharmaceutical Technology. (Swarbrick, J. and Boylan, J.C., eds.), Vol. 9, Marcel Dekker, NY pp. 1–39 (1994).

Shmeeda, H.R., Golden, E.B. and Barenholz, Y., Membrane lipids and aging. In: Handbook of Biomembranes: Structural and Functional Aspects, Vol. 2. (Shinitzky, M., ed.), Balaban Publ. VCH, Weinheim, pp. 1–82 (1994).

Bolotin, E.M., Cohen, R., Bar, L.K., Emanuel, N., Ninio, S., Lasic, D.D. and Barenholz, Y., Ammonium sulfate gradients for efficient and stable remote loading of amphipathic weak bases into liposomes and ligandoliposomes. J. Liposome Res. 4, 455–479 (1994).

Gabizon, A., Uziely, B., Kaufman, B., Safra, T., Catane, R. and Barenholz, Y., A new generation of Doxorubicin-loaded liposomes with improved localization in tumors: preclinical and clinical studies. In: Cancer Treatment, an Update. (Banzet, P., Holland, J.F., Khayat, D. and Weil, M., eds.), SpringerVerlag Press, pp. 820–822 (1994).

Gabizon, A., Catane, R., Uziely, B., Kaufman, B., Safra, T., Cohen, R., Martin, F., Huang, A. and Barenholz, Y., Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes. Cancer Res. 54, 987–992 (1994).

Kedar, E., Rutkowski, Y., Braun, E., Emanuel, N. and Barenholz, Y., Delivery of cytokines by liposomes. I. Preparation and characterization of interleukin2 encapsulated in long-circulating sterically stabilized liposomes. J. Immunother. 16, 47–59 (1994).

Kedar, E., Braun, E., Rutkowski, Y., Emanuel, N. and Barenholz, Y., Delivery of cytokines by liposomes. II. Interleukin2 encapsulated in long-circulating sterically stabilized liposomes: immunomodulatory and antitumor activity in mice. J. Immunother. 16, 115–124 (1994).

Caplan, S., Gallily, R. and Barenholz, Y., Characterization and purification of a mycoplasma membranederived macrophage-activating factor. Cancer Immunol. Immunother. 39, 27–33 (1994).

Shmeeda, H., Petkova, D. and Barenholz, Y., Cholesterol homeostasis in cultures of rat heart myocytes: relationship to cellular hypertrophy. Am. J. Physiol. 267 (Heart Circl. Physiol. 36) H1689–H1697 (1994).

Gabizon, A., Isacson, R., Libson, E., Kaufman, B., Uziely, B., Catane, R., Gera Ben Dor, C., Rabello, E., Cass, Y., Peretz, T., Sulkes, A., Chisin, R. and Barenholz, Y., Clinical studies of liposomal encapsulated doxorubicin. Acta Oncol. 3, 779–786 (1994).

Levy, M.Y., Polacheck, I., Barenholz, Y. and Benita, S., Efficacy evaluation of a novel submicron miconazole emulsion in a murine cryptococcosis model. Pharm. Res. 12, 223–230 (1995).

Shmeeda, H., Petkova, D. and Barenholz, Y: Cholesterol distribution in rat heart myocytes. Amer. J. Physiol. 268 (Heart Circl. Physiol. 37) H759–H766 (1995).

Begers, J.J., Van Bloois, L., Barenholz, Y. and Crommelin, D., Conformational changes of Myoglobin upon interaction with negatively-charged phospholipid vesicles. J. Liposome Res. 5, 311–326 (1995).

Lasic, D.D., Ceh, B., Stuart, M.C.A., Guo, L., Frederik, P.M. and Barenholz, Y., Transmembrane gradient driven phase transitions within vesicles: lessons for drug delivery. Biochim. Biophys. Acta 1239, 145–156 (1995).

Barenholz, Y. and Cohen, R., Rational design of amphiphile-based drug carriers and sterically stabilized carriers. J. Liposome Res. 5, 905–932 (1995).

Zuidam, N.J., Gouw, H.K.M.E., Barenholz, Y. and Crommelin, D.J.A., Physical (in)stability of liposomes upon chemical hydrolysis: the role of lysophospholipids and fatty acids. Biochim. Biophys. Acta 1240, 101–110 (1995).

Gabizon, A., Huang, A., Martin, F. and Barenholz, Y., Doxorubicin encapsulated in polyethylene glycolcoated liposomes: Initial clinical-pharmacokinetic studies in solid tumors. In: Stealth Liposomes. (Lasic, D.J. and Martin, F., eds.), CRC Press, Boca Raton, FL, pp. 245–255 (1995).

Böhm, W., Schirmbeck, R., Elbe, A., Melber, K., Diminsky, D., Kraal, G., van Rooijen, N., Barenholz, Y. and Reimann, J., Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo. J. Immunol. 155, 3313–3321 (1995).

Adler, A., Schachter, J., Barenholz, Y., Bar, L.K., Klein, T., Korytnaya, R., Sulkes, A., Michowiz, R., Cohen, Y. and Kedar, I., Allogeneic human liposomal melanoma vaccine with or without IL2 in metastatic melanoma patients: clinical and immunobiological effects. Cancer Biother. 10, 293–306 (1995).

Clerc, S. and Barenholz, Y., Loading of amphipathic weak acids into liposomes in response to transmembrane calcium acetate gradients. Biochim. Biophys. Acta 1240, 257–265 (1995).

Barenholz, Y., Optimization of amphiphile-based colloidal carriers. In: Handbook of Nonmedical Applications of Liposomes, Vol. III. (Barenholz, Y. and Lasic, D.D., eds.), CRC Press, Boca Raton, FL, pp. 1–3 (1996).

Emanuel, N., Kedar, E., Toker, O., Bolotin, E. and Barenholz, Y., Steric stabilization of liposomes improves their use in diagnostics. In: Handbook of Nonmedical Applications of Liposomes, Vol. IV. (Barenholz, Y. and Lasic, D.D., eds.), CRC Press, Boca Raton, FL, pp. 229–243 (1996).

Barenholz, Y. and Lasic, D.D., An overview of liposome scaled-up production and quality control. In: Handbook of Nonmedical Applications of Liposomes, Vol. III. (Barenholz, Y. and Lasic, D.D., eds.), CRC Press, Boca Raton, FL, pp. 23–30 (1996).

Lasic, D.D. and Barenholz, Y., Liposomes: Past, present and future. In: Handbook of Nonmedical Applications of Liposomes, Vol. IV. (Barenholz, Y. and Lasic, D.D., eds.), CRC Press, Boca Raton, FL, pp. 299–315 (1996).

Kalmanzon, E., Zlotkin, E. and Barenholz, Y., Liposomes as a model system to study shark repellency. In: Handbook of Nonmedical Applications of Liposomes, Vol. IV. (Barenholz, Y. and Lasic, D.D., eds.), CRC Press, Boca Raton, FL, pp. 183–198 (1996).

Barenholz, Y., Cohen, T., Haas, E. and Ottolenghi, M., Lateral organization of pyrene-labeled lipids in bilayers as determined from the deviation from equilibrium between pyrene monomers and excimers. J. Biol. Chem. 207, 3085–3090 (1996).

Pop, E., Liu, Z.Z., Brewster, M.E., Barenholz, Y., Korablyov, V., Mechoulam, R., Nadler, V. and Biegon, A., Derivatives of Dexanabinol. I. Watersoluble salts of glycinate esters. Pharm. Res. 13, 62–69 (1996).

Pop, E., Soti, F., Brewster, M.E., Barenholz, Y., Korablyov, V., Mechoulam, R., Nadler, V. and Biegon, A., Derivatives of Dexanabinol. II. Salts of amino acid esters containing tertiary and quaternary heterocyclic nitrogen with increased water-solubility. Pharm. Res. 13, 469–475 (1996).

Emanuel, N., Kedar, E., Bolotin, E.M., Smorodinsky, N.I. and Barenholz, Y., Preparation and characterization of doxorubicin-loaded sterically stabilized immunoliposomes. Pharm. Res. 13, 352–359 (1996).

Tirosh, O., Katzhendler, Y., Barenholz, Y., Ginsburg, I.and Kohen, R., Antioxidant properties of amidothionophosphates: novel antioxidant molecules. Free Radicals Biol. Med. 20, 421–432 (1996).

Barenholz, Y., Bolotin, E., Cohen, R. and Gabizon, A., Sterically stabilized doxorubicin-loaded liposomes (DOXSL™): From basics to the clinics. In: Phosphorus, Sulfur, and Silicon and the Related Elements. (Holmes, R.R., ed.), pp. 109–110, pp. 293–296 (1996).

Emanuel, N., Kedar, E., Bolotin, E.M., Smorodinsky, N.I. and Barenholz, Y., Targeted delivery of doxorubicin via sterically stabilized immunoliposomes: pharmacokinetics and biodistribution in tumor-bearing mice. Pharm. Res. 13, 861–868 (1996).

Diminsky, D., Reimann, Z.J., Schirmbeck, R. and Barenholz, Y., Structural and functional characterization of liposomal recombinant hepatitis B vaccine. J. Liposome Res. 6, 289–304 (1996).

Zomber, G., Bogin, E. and Barenholz, Y., Effect of i.v. injection of small unilamellar liposomes of egg phosphatidylcholine on cholesterol in plasma and erythrocytes, serum enzymes and liver function in dogs. J. Liposome Res. 6, 455–477 (1996).

Levy, M.Y., Polacheck, I., Barenholz, Y. and Benita, S., The design and evaluation of a novel submicron amphotericin B emulsion in systemic murine cryptococcosis. In: Surfactants in Solutions. (Chattopadhyay, A.K. and Mittal, K., eds.), Marcel Dekker, NY, pp. 345–366 (1996).

Glick, D. and Barenholz, Y., IgG immunoglobulins induce activation of the sphingomyelin cycle in HL60 cells. FEBS Lett. 394, 237–240 (1996).

Eckstein, M., Barenholz, Y., Bar, L.K. and Segal, E., Liposomes containing Candida albicans ribosomes as a prophylactic vaccine against disseminated Candidiasis in mice. Vaccine 15, 220–224 (1997).

Samuni, A.M. and Barenholz, Y., Stable nitroxide radicals protect lipid acyl chains from radiation damage. Free Radicals Biol. Med. 22, 1165–1174 (1997).

Diminsky, D., Schirmbeck, R., Reimann, J. and Barenholz, Y., Comparison between hepatitis B surface antigen (HBsAg) particles derived from mammalian cells (CHO) and yeast cells (Hansenula polymorpha): composition, structure and immunogenicity. Vaccine 15, 637–647 (1997).

Tirosh, O., Kohen, R., Katzhendler, J., Gorodetsky, R. and Barenholz, Y., Novel synthetic phospholipid protects lipid bilayers against oxidative damage: role of hydration layer and bound water. J. Chem. Soc., Perkin Trans. 2, 383–389 (1997).

Kedar, E., Palgi, O., Golod, G., Babai, I. and Barenholz, Y., Delivery of cytokines by liposomes. III. Liposome-encapsulated GMCSF and TNFa show improved pharmacokinetics and biological activity and reduced toxicity in mice. J. Immunother. 20, 180–193 (1997).

Bar, L.K., Barenholz, Y. and Thompson, T.E., The effect of sphingomyelin composition on the phase structure of phosphatidylcholine-sphingomyelin bilayers. Biochemistry 36, 2507–2516 (1997).

Tirosh, O., Kohen, R., Katzhendler, J., Alon, A. and Barenholz, Y., Oxidative stress effect on the integrity of lipid bilayers is modulated by cholesterol level of bilayers. Chem. Phys. Lipids 87, 17–22 (1997).

Felgner, P.L., Barenholz, Y., Behr, J.P., Cheng, S.H., Cullis, P., Huang, L., Jessee, J.A., Seymour, L., Szoka, F., Thierry, A.R., Wanger, E. and Wu, G., Nomenclature for synthetic gene delivery systems. Hum. Gene Ther. 8, 511–512 (1997).

Samuni, A.M., Barenholz, Y., Crommelin, D.J.A. and Zuidam, N.J: gIrradiation damage to liposomes differing in composition and their protection by nitroxides. Free Radicals Biol. Med. 23, 972–979 (1997).

Zuidam, N.J. and Barenholz, Y., Electrostatic parameters of cationic liposomes commonly used for gene delivery as determined by 4heptadecyl7hydroxycoumarin. Biochim. Biophys. Acta 1329, 211–222 (1997).

Kedar, E. and Barenholz, Y., Delivery of cytokines by liposomes: A means of improving their immunomodulatory and antitumor activity. In: The Biotherapy of Cancer: From Immunotherapy to Gene Therapy. (Chouaib, S., ed.), INSERM, Paris, pp. 333–362 (1998).

Samuni, A.M., Crommelin, D.J.A., Zuidam, N.J. and Barenholz, Y., Differential scanning calorimetry: a tool to assess physical and chemical alterations in liposomes. J. Therm. Anal. 51, 37–48 (1998).

Zuidam, N.J. and Barenholz, Y., Electrostatic and structural properties of plasmid DNA–lipid complexes commonly used for gene delivery. Biochim. Biophys. Acta 1368, 115–128 (1998).

Gabizon, A., Goren, D., Cohen, R. and Barenholz, Y., Development of liposomal anthracyclines: from basics to clinical applications. J. Controlled Release 53, 275–279 (1998).

HirschLerner, D. and Barenholz, Y., Probing DNA–cationic lipid interactions with the flurophore trimethylammonium diphenylhexatriene (TMADPH). Biochim. Biophys. Acta 1370, 17–30 (1998).

Tirosh, O., Barenholz, Y., Katzhendler, Y., and Priev, A., Hydration of polyethylene glycol-grafted liposomes. Biophys. J. 74, 1371–1379 (1998).

Clerc, S., and Barenholz, Y., A quantitative model for using acridine orange as a transmembrane pH gradient probe. Anal. Biochem. 259, 104–111 (1998).

Barenholz, Y., Design of liposome-based drug carriers: From basic research to application as approved drugs. In: Medical Applications of Liposomes (Lasic, D.D. and Papahadjopoulos, D., eds.), Elsevier Science, Amsterdam, pp. 541–565 (1998).

Moses, A.E., Rahav, G., Barenholz, Y., Elidan, J., Azaz, B., Gillis, S., Brickman, M., Polacheck, I., Shapiro, M., Rhinocerebral mucormycosis treated with amphotericin B colloidal dispersion in three patients. Clin. Infect. Dis. 26, 1430–1433 (1998).

Priev, A., Samuni, A.M., Tirosh, O. and Barenholz, Y., The role of hydration in stabilization of liposomes; resistance to oxidative damage of PEG-grafted liposomes. In: Targeting of Drugs: Strategies for Stealth Therapeutic Systems. (Gregoriadis, G., McCormack, B., eds.), Plenum, NY, 147–167 (1998).

HirschLerner, D., Zuidam, N.J., and Barenholz, Y., Physicochemical characterization of DOTAPcontaining lipoplexes by fluorescent probes: relevance to lipofection. In: Targeting of Drugs. Strategies for Stealth Therapeutic Systems. (Gregoriadis, G. and McCormack, B., eds.), Plenum, NY, pp. 169–183 (1998).

Frankenberg, S., Glick, D., Klaus, S., and Barenholz, Y., Efficacious topical treatment for murine cutaneous leishmaniasis with ethanolic formulations of amphotericin B. Antimicrobial Agents and Chemotherapy. 42, 3092–3096 (1998).

Gabizon, A., and Barenholz, Y.: Liposomal anthracyclines — from basics to clinical approval of PEGylated liposomal doxorubicin. In: Liposomes: Rational Design. (Janoff, A.S., ed.), Marcel Dekker, NY, pp. 343–362 (1999).

Babai, I., Samira, S., Barenholz, Y., ZakaiRones, Z., and Kedar, E., A novel influenza subunit vaccine composed of liposome-encapsulated haemagglutinin/ neuraminidase and IL2 or GMCSF. I. Vaccine characterization and efficacy studies in mice. Vaccine 17, 1223–1238 (1999).

Babai, I., Samira, S., Barenholz,, Y., ZakaiRones, Z., and Kedar, E., A novel influenza subunit vaccine composed of liposome-encapsulated haemagglutinin/ neuraminidase and IL2 or GMCSF. II. Induction of TH1 and TH2 responses in mice. Vaccine 17, 1239–1250 (1999).

Korabylov, V., Zimran, A., and Barenholz, Y., Cerebroside-b-glucosidase encapsulation in liposomes for Gaucher's disease treatment revisited. Pharm. Res. 16, 466–469 (1999).

Cabanes, A., EvenChen, S., Zimberof, J., Barenholz, Y., Kedar, E. and Gabizon, A., Enhancement of antitumor activity of polyethylene glycolcoated liposomal doxorubicin with soluble and liposomal interleukin 2. Clin. Cancer Res. 5, 687–693 (1999).

Tirosh, O., Katzhendler, Y., Barenholz, Y. and Kohen, R., Antioxidant activity of amidothionophosphates. Methods Enzymol. 299, 293–300 (1999).

Bandak, S., Ramu, A., Barenholz, Y. and Gabizon, A., Reduced UV-induced degradation of doxorubicin encapsulated in polyethylene glycolcoated liposomes. Pharm. Res. 16, 841–846 (1999).

Zuidam, N.J. and Barenholz, Y., Characterization of DNA–lipid complexes commonly used for gene delivery. Int. J. Pharm. 183, 43–46 (1999).

Naslavsky, N., Shmeeda, H., Friedlander, G., Yanai, A., Futerman, A.H., Barenholz, Y. and Taraboulos, A., Sphingolipid depletion increases formation of the scrapie prion protein in neuroblastoma cells infected with prions. J. Biol. Chem. 274, 20763–20771 (1999).

Diminsky, D., Moav, N., Gorecki, M. and Barenholz, Y., Physical, chemical and immunological stability of CHOderived hepatitis B surface antigen (HBsAg) particles. Vaccine 18, 3–17 (1999).

Zuidam, N.J., HirschLerner, D., Margulies, S. and Barenholz, Y., Lamellarity of cationic liposomes and mode of preparation of lipoplexes affect transfection efficiency. Biochim. Biophys. Acta 1419, 207–220 (1999).

Barenholz, Y. and Thompson, T.E., Sphingomyelin: biophysical aspects. Chem. Phys. Lipids 102, 29–34 (1999).

Samet (Glick), D. and Barenholz, Y., Characterization of acidic and neutral sphingomyelinase activities in crude extracts of HL60 cells. Chem. Phys. Lipids 102, 65–77 (1999).

Zuidam, N.J., Barenholz, Y. and Minsky, A., Chiral DNA packaging in DNAcationic liposome assemblies. FEBS Lett. 457, 419–422 (1999).

HirschLerner, D. and Barenholz, Y., Hydration of lipoplexes commonly used in gene delivery: followup by laurdan fluorescence changes and quantification by differential scanning calorimetry. Biochim. Biophys. Acta 1461, 47–57 (1999).

Tirosh, O., Katzhendler, J., Barenholz, Y. and Kohen, R., Elucidation of the mechanism of LDL oxidation and of its prevention by amidothionophosphates, a new group of antioxidants. Antioxidants Redox Signalling, 1, 325–338 (1999).

Vardy, D., Barenholz, Y., Cohen, R., Zvulunov, A., Klaus, S. and Frankenburg, S. Topical amphotericin B for cutaneous leishmaniasis. Arch. Dermatol. 135, 856–857 (1999)

Barenholz, Y. and Cevc, G., Structure and properties of membranes. In Physical Chemistry of Biological Surfaces (Baszkin, A. and Norde, W., eds.), Marcel Dekker, NY (2000) pp. 171–241.

Kedar, E., Gur, H., Babai, I., Samira, S., EvenChen, S. and Barenholz, Y., Delivery of cytokines by liposomes. IV. Hematopoietic and immunomodulatory activity of interleukin2 encapsulated in conventional liposomes and in long-circulating liposomes. J. Immunother. 23, 131–145 (2000).

Barenholz, Y., Liposomology. Prog. Lipid Res. 39, 1–2 (2000).

Meidan, V.M., Cohen, J.S., Amariglio, N., HirschLerner, D. and Barenholz, Y., Interaction of oligonucleotides with cationic lipids: the relationship between electrostatics, hydration and state of aggregation. Biochim. Biophys. Acta 1464, 251–261 (2000).

Simberg, D., HirschLerner, D., Nissim, R. and Barenholz, Y., Comparison of different commercially available cationic lipidbased transfection kits. J. Liposome Res. 10, 1–13 (2000).

Samuni, A., Lipman, A. and Barenholz, Y., Damage to liposomal lipids: protection by antioxidants and cholesterolmediated dehydration. Chem. Phys. Lipids 105, 121–134 (2000).