Oxygen-stable hemolysins of group A streptococci. V. Effect on rat heart and kidney cells grown in tissue culture

Citation:

Z. Marcus, Davies, AM. , and Ginsburg, Isaac . 1966. “Oxygen-Stable Hemolysins Of Group A Streptococci. V. Effect On Rat Heart And Kidney Cells Grown In Tissue Culture”. Experimental And Molecular Pathology, 5, Pp. 93-107.

Abstract:

The effects of streptolysin S and cell-bound hemolytic factor were tested on tissue cultures of rat heart and kidney. Cytopathogenic changes were observed, characterized by swelling, cytoplasmic vacuolization and bleb formation and cells were disintegrated within 1–2 hours. These changes were abolished by known inhibitors of streptolysin S.