The effect of leukocyte hydrolases on bacteria. XI. Lysis by leukocyte extracts and by myeloperoxidase of a Staphylococcus aureus mutant which is deficient in teichoic acid, and the inhibition of bacteriolysis by lipoteichoic acid

Citation:

Michael N Sela, Ofek, Itzhak , Lahav, Meir , and Ginsburg, Isaac . 1978. “The Effect Of Leukocyte Hydrolases On Bacteria. Xi. Lysis By Leukocyte Extracts And By Myeloperoxidase Of A Staphylococcus Aureus Mutant Which Is Deficient In Teichoic Acid, And The Inhibition Of Bacteriolysis By Lipoteichoic Acid”. Proceedings Of The Society For Experimental Biology And Medicine. Society For Experimental Biology And Medicine, 159, Pp. 126-130.

Abstract:

A Staph, aureus mutant (52A5) which is deficient in wall teichoic acid (TA) was found to be highly susceptible to lysis by leukocyte extracts (ENZ) and by myeloperoxidase (MPO) when harvested from the stationary phase of growth, On the other hand, a staphylococcus mutant, which is deficient in N-acetyl glucosamine in its TA (52A2), the parent strain SH and a protein A rich strain Cowen I, could be lysed by the leukocyte factors only when harvested from the logarithmic phase of growth.