Inflammatory Bowel Diseases

 

The SysmedIBD Research Consortium:  http://www.sysmedibd.eu/home/                                                                  

 

sysmed_timeline

 

Human gut xenograft in SCID mice:

Human gut xenograft

 

Human gut xenograft model

 

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Pathogenesis of enteropathogens in the human gut

 

Enteropathogens

 

Genome-wide comparative transcriptome analysis of steady state and inflamed human and mouse gut

berlin_2016Berlin 2016  

 

ibd_1

 

A novel in vivo platform for the evaluation of new therapies for Crohn’s disease fistulae

IBD_Award

 

Research aims:

  1. Pharmacodynamics of anti TNF in normal and fistulating human gut xenografts.
  2. Therapeutic effect of anti TNF on gut fistula in the model.
  3. Therapeutic effect of allogeneic human MSCs on gut fistula in the model.

IBD_2