Citation:
G Marone, Spadaro, G, Braile, M, Poto, R, Criscuolo, G, Pahima, H, Loffredo, S, Levi-Schaffer, F, ו Varricchi, G. 2019. “Tezepelumab: A Novel Biological Therapy For The Treatment Of Severe Uncontrolled Asthma”. Expert Opin Investig Drugs, 28, 11, Pp. 931–940.
תקציר:
: TSLP is a promising target for T2-high and perhaps some patients with T2-low asthma. The results of preliminary clinical trials are encouraging. Several unanswered questions concerning basic pathophysiological aspects of TSLP variants, the long-term safety and efficacy of tezepelumab with different phenotypes/endotypes of asthma should be addressed.