Citation:
O Tepper, Zheng, H, Appella, DH, ו Yavin, E. 2021. “Cyclopentane Fit-Pnas: Bright Rna Sensors”. Chem Commun (Camb), 57, 4, Pp. 540–543.
תקציר:
Cyclopentane modified FIT-PNA (cpFIT-PNA) probes are reported as highly emissive RNA sensors with the highest reported brightness for FIT-PNAs. Compared to FIT-PNAs, cpFIT-PNAs have improved mismatch discrimination for several pyrimidine-pyrimidine single nucleotide variants (SNVs).