A Staph, aureus mutant (52A5) which is deficient in wall teichoic acid (TA) was found to be highly susceptible to lysis by leukocyte extracts (ENZ) and by myeloperoxidase (MPO) when harvested from the stationary phase of growth, On the other hand, a staphylococcus mutant, which is deficient in N-acetyl glucosamine in its TA (52A2), the parent strain SH and a protein A rich strain Cowen I, could be lysed by the leukocyte factors only when harvested from the logarithmic phase of growth.
The effect of leukocyte hydrolases on bacteria - XII. The release of lipopolysaccharide (LPS) from Salmonella typhi by leukocyte extracts, lysozyme, inflammatory exudates and by serum and synovial fluid and the modulation by anionic and cationic polyelectrolytes of LPS release and the sensitization of erythrocytes
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