@article {Cohen2024,
	title = {Resolving transitions between distinct phases of memory consolidation at high resolution in Caenorhabditis elegans},
	journal = {iScience},
	volume = {27},
	year = {2024},
	month = {11},
	pages = {111147},
	publisher = {Elsevier},
	abstract = {SummaryMemory consolidation following learning is a dynamic and complex process comprising several transitions between distinct memory phases. Although memory consolidation has been studied extensively, it remains difficult to draw an integral description that can delimit the transition points between specific memory phases at the behavioral, neuronal, and genetic levels. To this end, we have developed a rapid and robust aversive conditioning protocol for the nematode worm Caenorhabditis elegans, tracing memory consolidation within the first hour post conditioning and then up to 18 h post conditioning. This made it possible to uncover time-dependent involvement of primary sensory neurons, transcription and translation processes, and diverse gene populations in memory consolidation. The change in neuronal valence was strong enough to induce second order conditioning, and was amenable to considerable modulation in specific mutant strains. Together, our work lends memory consolidation to detailed temporal and spatial analysis, advancing system-wide understanding of learning and memory.},
	keywords = {Cognitive neuroscience, Molecular neuroscience, neuroscience, omics},
	issn = {2589-0042},
	doi = {10.1016/J.ISCI.2024.111147},
	url = {http://www.cell.com/article/S2589004224023721/fulltext http://www.cell.com/article/S2589004224023721/abstract https://www.cell.com/iscience/abstract/S2589-0042(24)02372-1},
	author = {Netanel Cohen and Rabinowitch, Ithai}
}
