Prof. Esti Shohami

Prof. Esti
Shohami
School of Pharmacy, The Faculty of Medicine The Hebrew University of Jerusalem, Ein Karem P.O.Box ,Jerusalem 91120, Israel
Research Interest: Prof. Shohami’s research focuses on traumatic brain injury (TBI) and addresses the pathophisiology of TBI. She studies the mechanisms of injury (e.g. inflammation, oxidative stress, the glutamate NMDA receptors) as well as endogenous injury-induced neuroprotective brain mechanisms (e.g. erythropoietin, endocannabinoids, and heat-acclimation-induced preconditioning). She has published more than 220 articles, reviews and book chapters, and is a collaboraor at several patents. At her University Prof. Shohami teaches neuropharmacology to medical and pharmacy students and has supervised over 40 students forMSc,MDand PhD. She holds several duties at the administrative levels of the University, and also at National science committees.  Current Research Topics:  Pathophysiology of TBI: neurochemical changes and neurobehavioral impairments. Special emphasis on leaning and memory deficits after TBI and attempts to repair them via genetic manipulations, pharmacological intervention and/or training. The (endo)cannabinoid system: its role in the healthy and injured brain Activation, rather than inhibition of the glutamate NMDA receptor is protective after TBI and neuroinflammation: exploring the mechanism by which activation of down-regulated NMDAR may restore its function.