Citation:
E Touitou, Natsheh, H, Boukeileh, S, ו Awad, R. 2021. “Short Onset And Enhanced Analgesia Following Nasal Administration Of Non-Controlled Drugs In Nanovesicular Systems”. Pharmaceutics, 13, 7.
תקציר:
was three-fold higher relative to oral administration of this drug. In the experiment testing analgesia, a rapid and improved analgesia was observed for the tested drugs when delivered nasally in the nanocarrier. On the other hand, a weaker analgesic effect was observed for oral and nasal control systems. This new approach suggests that nasal delivery of non-controlled drugs in soft nanovesicles may open the way for better and noninvasive treatment of severe pain.