@article {62840,
	title = {Anti-inflammatory ketoprofen in the treatment of field cases of bovine mastitis},
	journal = {Res Vet SciRes Vet SciRes Vet Sci},
	volume = {56},
	number = {1},
	year = {1994},
	note = {Shpigel, N YChen, RWinkler, MSaran, AZiv, GLongo, FengClinical TrialRandomized Controlled TrialENGLAND1994/01/01Res Vet Sci. 1994 Jan;56(1):62-8.},
	month = {Jan},
	pages = {62-8},
	abstract = {The efficacy of ketoprofen in the treatment of acute clinical mastitis was evaluated in a clinical trial comprising a non-blind controlled study and a blind, placebo-controlled study. All the cows were treated with 20 g sulphadiazine and 4 g trimethoprim intramuscularly upon diagnosis, and half the dosage was given once daily thereafter. In addition, the ketoprofen treatment groups received 2 g ketoprofen intramuscularly once daily for the duration of the antimicrobial therapy. Recovery rates for the non-blind contemporary controls and the blind placebo-controls were 83.7 per cent and 70.7 per cent, respectively. In the non-blind controlled ketoprofen and the placebo-controlled ketoprofen treatment groups, recovery rates were 94.7 per cent and 92.3 per cent, respectively. The odds ratio (OR) of recovery was significantly (P < or = 0.01) high in the placebo-controlled study (OR = 6.75, confidence interval [CI] = 1.45 to 31.4), and high but not significant in the non-blind controlled study (OR = 2.64, CI = 0.53 to 13.10). It was concluded that ketoprofen significantly improved recovery in clinical mastitis in dairy cows.},
	keywords = {Animals, Cattle, Drug Combinations, Female, Ketoprofen/*therapeutic use, Mastitis, Bovine/*drug therapy, Single-Blind Method, Sulfadiazine/therapeutic use, Trimethoprim/therapeutic use},
	isbn = {0034-5288 (Print)0034-5288 (Linking)},
	author = {Shpigel, N. Y. and Chen, R. and Winkler, M. and Saran, A. and Ziv, G. and Longo, F.}
}
