@article {1429177, title = {α-Borylalkyl Radicals: Their Distinctive Reactivity in Modern Organic Synthesis}, journal = {Chemical Communications}, year = {2020}, pages = {13-25}, abstract = {

Organoborons are extremely important for synthetic organic chemistry; they can serve as advanced intermediates for a variety of transformations. Such a well-known transformation involves the loss of the boron moiety, creating alkyl radicals. Although these originally developed protocols for alkyl radical generation remain in active use today, in recent years their α-boryl carbon-centred radicles have been joined by a new array of radical generation strategies that offer a unique reactivity to forge a wider diversity of organoborones that often operate under mild and benign conditions. Herein, we will highlight the stability and reactivity of α-borylalkyl radicals and their remarkably recent advances in order to further utilise them for C{\textendash}C and C{\textendash}heteroatom bond formation. Their use for this purpose has been reported over the last decade in an attempt to guide the synthetic community. Various transition-metal and metal-free methods for their generation are presented, and more advanced photoredox approaches are discussed, mainly for the period of time 2009-2019.

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}, url = {https://pubs.rsc.org/en/content/articlelanding/2019/cc/c9cc08027a}, author = {Nivesh Kumar and Reddy Rajasekhar Reddy and Nadim Eghbarieh and Ahmad Masarwa*} }