@article {2943,
	title = {SUN-domain and KASH-domain proteins during development, meiosis and disease.},
	journal = {Cell Mol Life Sci},
	volume = {66},
	year = {2009},
	month = {2009 May},
	pages = {1518-33},
	abstract = {SUN-domain proteins interact directly with KASH-domain proteins to form protein complexes that connect the nucleus to every major cytoskeleton network. SUN-KASH protein complexes are also required for attaching centrosomes to the nuclear periphery and for alignment of homologous chromosomes, their pairing and recombination in meiosis. Other functions that require SUN-domain proteins include the regulation of apoptosis and maturation and survival of the germline. Laminopathic diseases affect the distribution of the SUN-KASH complexes, and mutations in KASH-domain proteins can cause Emery Dreifuss muscular dystrophy and recessive cerebellar ataxia. This review describes our current knowledge of the role of SUN-KASH domain protein complexes during development, meiosis and disease.},
	keywords = {Amino Acid Motifs, Animals, Apoptosis, Biological, Cell Nucleus, Centrosome, Cerebellar Ataxia, Chromosomes, Cytoskeleton, Emery-Dreifuss, Humans, Lamins, Meiosis, Membrane Proteins, Models, Muscular dystrophy},
	issn = {1420-9071},
	doi = {10.1007/s00018-008-8713-y},
	author = {Fridkin, A and Penkner, A and Jantsch, V and Gruenbaum, Y}
}
