@article {17015,
	title = {Effect of occlusal (mechanical) stimulus on bone remodelling in rat mandibular condyle},
	journal = {J Oral Pathol},
	volume = {16},
	number = {8},
	year = {1987},
	note = {Gazit, D Ehrlich, J Kohen, Y Bab, I eng Denmark 1987/09/01 J Oral Pathol. 1987 Sep;16(8):395-8.},
	pages = {395-8},
	type = {Journal Article},
	abstract = {Mechanical load influences the remodelling of skeletal tissues. In the mandibular condyle, occlusal alterations and the consequent mechanical stimulus induce changes in chondrocytes and cartilage mineralization. In the present study we quantified in the mandibular condyle the effect of occlusal interference on remodelling of the subchondral bone. Computerized histomorphometry after 5-21-day exposure to the influence of a unilateral occlusal splint revealed an increased rate of trabecular remodelling, consisting of enhancement in osteoblast and osteoclast numbers and activities. The bone formation parameters reached their high values on Days 5 or 9 and remained stable thereafter. Bone resorption showed a gradual increase throughout the experimental period. These results further characterize the temporomandibular joint reaction to occlusal alterations. It is suggested that the present increase in bone turnover together with the known enhancement in chondrogenesis are part of a process of functional adaptation in response to mechanical stimulus.},
	keywords = {Animals Bone Resorption/pathology/physiopathology Cartilage/pathology/*physiopathology Dental Occlusion, Inbred Strains Stress, Mechanical Time Factors, Traumatic/pathology/*physiopathology Male Mandibular Condyle/pathology/*physiopathology Osteogenesis Rats Rats},
	issn = {0300-9777 (Print) 0300-9777 (Linking)},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/3121824},
	author = {Gazit, D. and Ehrlich, J. and Kohen, Y. and Bab, I.}
}
